Research Article

Related GMR Articles

05/31/2011
Body measurement traits; Cattle; GDF10 gene; SNP

Body measurement traits are known to play numerous important roles in the assessment of productivity and economic value. They are influenced by several factors, among which genetic factors are predominant. The gene GDF10 is involved in skeletal morphogenesis and is associated with body measurement traits. It may be an important candidate gene for marker-assisted selection. We ... more

C. Adoligbe; L.S. Zan; H.B. Wang; J.A. Ujjan
10/19/2010
IL-6; Insulin resistance; SNP; TCF7L2; TNF; VDR

A population-based study was undertaken to evaluate linkage between single-nucleotide polymorphisms known as risk factors and type 2 diabetes in an Indian population. The study population was comprised of 40 normal glucose-tolerant individuals (21 males and 19 females) and 40 type 2 diabetes patients (21 males and 19 females). The genes and their corresponding single-nucleotide ... more

P.N. Mukhopadhyaya; A. Acharya; Y. Chavan; S.S. Purohit; A. Mutha
08/31/2010
Cattle; Meat quality traits; MYPN gene; PCR-RFLP; SNP

Myopalladin (MYPN) is a multifunctional protein that maintains sarcomeric integrity and regulates Z-line structure. It is an important candidate gene for meat quality selection through marker-assisted selection. Using PCR-RFLP technology, we discovered a single-nucleotide polymorphism (SNP) (A1795G in exon 9) of the MYPN gene. Allele frequencies of this SNP were investigated and evaluated ... more

Y. Jiao; L.S. Zan; Y.F. Liu; H.B. Wang; B.L. Guo
11/09/2010
Body measurement traits; Goat; LF gene; Milk composition; PCR-SSCP; SNP

Milk composition and body measurement traits, influenced by genes and environmental factors, play important roles in value assessments of efficiency and productivity in dairy goats. Lactoferrin (LF), involved in the efficient expression of protein in milk, is also an anabolic factor in skeletal tissue and a potent osteoblast survival factor. Therefore, it is an important candidate gene ... more

B.L. Guo; Y. Jiao; C. He; L.X. Wei; Z.H. Chang; X.P. Yue; X.Y. Lan; H. Chen; C.Z. Lei
10/19/2010
Beef cattle; Marker assisted selection; QTL; SNP; Zebu

We analyzed the polymorphisms TFAM HaeIII, TFAM MboI and FABP4 MspA1I in three Nellore lines selected for growth in order to evaluate how selection affects the frequencies of these polymorphisms and evaluate their association with growth and carcass traits in Zebu cattle. Birth, weaning and yearling weights, rump height, longissimus muscle area, backfat ... more

D.R. Ayres; F.R.P. Souza; M.E.Z. Mercadante; L.F.S. Fonseca; H. Tonhati; J.N.S.G. Cyrillo; S.F.M. Bonilha; L.G. Albuquerque
05/11/2010
ATP1A1 gene; Dairy cattle; Heat stress; K+-ATPase; Na+; SNP

Heat stress produces oxidative stress and affects the alternation of plasma K+ and Na+. Since Na+,K+-ATPase is sensitive to oxidative stress and critical for maintaining the homeostasis of these two ions, we examined the genetic polymorphism of the ATP1A1 gene in 160 Holstein cows using polymerase chain reaction low ionic strength ... more

Y.X. Liu; X. Zhou; D.Q. Li; Q.W. Cui; G.L. Wang
02/28/2013
Combined genotype; Goat; PCR-RFLP; SNP

Kisspeptins, the product of the KISS1 gene, play an essential role in the regulation of reproductive functions, acting primarily at the hypothalamic level of the gonadotropic axis. We detected polymorphisms of the goat KISS1 gene in 723 individuals from three goat breeds (Xinong Saanen, Guanzhong, and Boer) by DNA pooling, PCR-RFLP, and DNA sequencing methods. We cloned ... more

X.P. An; P. Han; J.X. Hou; H.B. Zhao; Y. Yan; T. Ma; F. Fang; F.X. Meng; Y.X. Song; J.G. Wang; B.Y. Cao
09/04/2013
Alpha-lactalbumin gene; Association analysis; Chinese Holstein cows; Milk production traits; SNP

The traits particularly important for milk production include milk yield, protein percentage, fat percentage, and the somatic cell score. Alpha-lactalbumin (α-LA) is an important whey protein of cow milk, and is also present in the milk of many other mammalian species. In this study, we analyzed the genetic polymorphisms of the α-LA gene and their relationship to milk production traits ( ... more

J.P. Zhou; C.H. Dong
05/13/2013
Clone; Duck; PCR-RFLP; PLIN gene; SNP

The perilipin (PLIN) gene is a candidate gene of carcass and fat traits in ducks. In order to study the molecular character of the PLIN gene and its function in different breeds of Chinese ducks, samples were obtained from the Chinese Academy of Agricultural Sciences Research Center for Birds, including 95 Peking ducks of the Z2 series, 91 Peking ducks of the Z4 series, ... more

H.L. Zhang; H.J. Fan; X.L. Liu; Y. Wu; S.S. Hou
03/13/2013
Allele; Gene; Jordan; MDR1; SNP

The multidrug resistance gene (MDR1 or ABCB1) codes for P-glycoprotein, which plays an important role in regulating absorption, distribution, and elimination of drugs. We examined MDR1 gene variants in 100 unrelated subjects from various regions of Jordan. The MDR1 gene was scanned using direct sequencing. Six rare variants in MDR1 were ... more

O.F. Khabour; K.H. Alzoubi; S.I. Al-Azzam; N.M. Mhaidat

Pages