Research Article

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Grape juices are an important source of food antioxidants. Unfortunately, there is little data about the mineral composition and the antioxidant, mutagenic and antimutagenic activities of grape juice in eukaryote cells. We evaluated the mineral contents (Mg, Ca, Mn, Fe, Cu, Zn, Si, S, Cl) of grape juices, the antioxidant, mutagenic and/or antimutagenic activities of the juices in the ... more

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J.R. Pesarini; S.G. Victorelli; A.P. Vicentini; L.K. Ferreira; M.O. Mauro; R. Matuo; J.R. Oliveira; A.C.M.B. Antoniolli; M.S. Mantovani; R.J. Oliveira
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Antioxidant; Inflammation; Mutation; Oxidative stress; Polymorphism; Small bowel

Celiac disease (CD) is a multifactorial, inflammatory small bowel disorder characterized by nutrient malabsorption resulting from mucosal damage, the latter induced by cereal products like barley, oat, and wheat. Oxidative stress has previously been reported to play an important role in the pathogenesis of CD. In the present study, we aimed to evaluate the frequency of polymorphisms that ... more

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Thunbergia laurifolia (TL) is widely used as an antidote in Thai traditional medicine against toxic substances such as alcohol, pesticides, arsenic, and strychnine. We found that the lyophilized form of TL in 80% ethanol possessed the antioxidant levels within the range 23,163.9 ± 1457.4 Trolox equivalents mM/kg dry mass and 899.8 ± 14.5 gallic acid equivalents mM/kg dry mass ... more

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Antioxidant; Expressed sequence tags; Free radicals; Oxidative stress; Paracoccidioides brasiliensis; Transcription factors

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Antioxidant; Comet assay; haptoglobin polymorphism; hydrogen peroxide

Human haptoglobin is classified into three major phenotypes: Hp1-1, Hp2-1 and Hp2-2; there are two autosomal alleles Hp*1 and Hp*2, and the Hp*1 allele has two subtypes, Hp*1F and Hp*1S. Haptoglobin acts as an antioxidant, preventing hemoglobin-driven oxidative damage. We used the comet assay to ... more

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Antioxidant; Lipid metabolism genes; Oxidative stress; Thai black sticky rice

Anthocyanins, which are found in some food, including Thai black sticky rice, are reported to have health-promoting properties. Oxidative stress plays a major role in the pathogenesis of many degenerative diseases induced by free radicals, such as cardiovascular disease, stroke and cancer. We evaluated the anthocyanin-rich extract (ARE) from Thai black sticky rice for antioxidative and ... more

W. Sangkitikomol; T. Tencomnao; A. Rocejanasaroj
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Meiosis; Moringa oleifera; Pollen viability; Tripolar spindles; Unreduced gametes

Although originally from India, Moringa oleifera is now cultivated throughout most of the tropics, including Brazil. Despite its multipurpose value for food and traditional medicine, little is known about the meiotic behavior and pollen viability of M. oleifera. We evaluated microsporogenesis and pollen viability in eleven plants grown in southern Brazil (Maringá, Paraná ... more

N. Silva; A.B. Mendes-Bonato; J.G.C. Sales; M.S. Pagliarini
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Haplotype; Kazakh; Linkage disequilibrium; Metabolic syndrome; Polymorphism; PPARγ

We investigated the relationship between haplotype and linkage disequilibrium of the PPARγ gene polymorphisms rs3856806, rs12490265, rs1797912, and rs1175543 and metabolic syndrome (MS) in the Kazakh people of Xinjiang Province. For PPARγ, rs3856806, rs12490265, rs1797912, and rs1175543 genotypes were detected in 489 subjects (including 245 MS patients and 244 controls) using matrix- ... more

S.X. Guo; H. Guo; R.L. Ma; Y.S. Ding; J.Y. Zhang; J.M. Liu; M. Zhang; Q. Niu; N. Qiang; S.G. Li; C.N. Qi

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