Research Article

Related GMR Articles

03/17/2006
Electrophoresis; Hemoglobin variants; HPLC; Laboratory diagnosis
Lde Souza Ondei
09/03/2013
Aflatoxin; Aspergillus flavus; HPLC; Inter-simple sequence repeats; Random amplified polymorphic DNA; Wheat

Twelve species belonging to six fungal genera were found to be associated with wheat (Triticum aestivum L.) grain samples collected from three main regions in Saudi Arabia. The most common genera (average frequency) were Aspergillus (14.3%), Fusarium (29.1%), Penicillium (9.3%), and Alternaria (8.2%). Nineteen isolates of Aspergillus flavus ... more

A.S. Al-Wadai; M.R. Al-Othman; M.A. Mahmoud; A.R.M.Abd El-Aziz
12/01/2006
Blood donors; Hb I-Philadelphia; HPLC; Rare hemoglobin

We describe a heterozygous case of Hb I-Philadelphia [alpha 16 (A14) LYS→GLU] in a blood donor from the Acre State Blood Bank, in the Brazilian Amazon region. We confirmed the mutation by electrophoretic and chromatographic methods and by DNA sequencing. A literature search showed that this is the first description of this alpha globin mutant in a Brazilian Caucasian group. We also emphasize ... more

F.R. Torres; L.S. Ondei; R.U. Silva; C.E. Cavasini; C.R. Bonini-Domingos; P.J.A. Zamaro; A.R.B. Rossit; R.L.D. Machado
03/09/2006
Biological monitoring; Exfoliated cells; Gas station attendants; Micronucleus test; Mutagenicity; Occupational exposure

In the present study, the micronucleus test was applied in exfoliated cells of buccal mucosa to assess the mutagenicity risk associated with occupational exposure for gas station attendants. For each individual, 2000 exfoliated buccal cells were analyzed for micronucleus frequency. A highly significant difference was found between exposed and control groups. Likewise, a significant ... more

C.Iribarrem Benites; L.Lund Amado; R.Aloma Pack Vianna; Mda Graça Martino-Roth
09/01/2009
Allium cepa; Hydrocotyle ranunculoides; Mutagenicity; Pelotas Creek

Water resource degradation is one of mankind’s greatest worries, as it causes direct and indirect damage to the associated biota. We initiated a water monitoring study in Pelotas Creek in 2003 in order to assess the mutagenic effect of the creek’s waters. Allium cepa cells exposed to water samples and a chronically exposed macrophyte were analyzed, through evaluation of the ... more

T.C.O. Santos; L.F. Maciel; K.S. Leal; A.E.N. Bender; T.S. Paiva; G.L. Garcias; M.G. Martino-Roth
03/17/2009
Allium cepa; Anomalies; Channel; Meristems; Mutagenicity

The São Gonçalo Channel is of great importance to the conservation of local biodiversity; it also is a water supply source of the city of Pelotas, Brazil, and the surrounding region. We examined the mutagenic activity of its waters. The following items were seasonally investigated in Allium cepa root radicular meristem cells: mitotic index, mitotic anomalies, interphase anomalies, and ... more

T.S. Paiva; G.L. Garcias; M.G. Martino-Roth
05/20/2008
chronic renal disease; hemodialysis patients; Micronucleus; Mutagenicity; peritoneal dialysis patients

Patients with chronic renal disease have an increased incidence of cancer. It is well known that long periods of hemodialysis treatment are linked to DNA damage due to oxidative stress. This genotoxic effect may cause the loss of chromosome fragments, or even entire chromosomes, which form micronuclei after cell division, and can be detected by the micronucleus test. In the present case- ... more

J.M. Roth; R.G. Restani; T.T.S. Gonçalves; S.L.S. Sphor; A.B. Ness; M.G. Martino-Roth; G.L. Garcias
01/18/2011
Antimutagenicity; Duguetia furfuracea; Genotoxicity; Mutagenicity

Mutagenic and antimutagenic activities of the medicinal plant Duguetia furfuracea were assessed using SMART/wing and ring-X-loss tests. For the ring-X-loss test, 2- to 3-day-old Drosophila melanogaster ring-X-lineage males and virgin ywsn3 females received D. furfuracea infusion at doses of 0.085, 0.042, or 0.014 g/mL for 24 h. We found that D. furfuracea ... more

L.S. Coelho; L.P. Felício; C.T. Miranda; C.R. Vale; D.C.S. Lima; S.R. Duarte; H.D. Ferreira; C. Chen; S. Carvalho; E.M. da Silva
09/27/2013
Mutagenicity; PAHs; Respirable particulate matter; Risk assessment; Salmonella/microsome assay

Risk assessment can provide a comprehensive estimate of potential effects of contaminants under specific, well-defined, and well-described circumstances, providing quantitative relationships between exposure and effects to identify and to define areas of concern. We investigated the mutagenic activity of particulate matter in air samples collected from three sites in Rio de Janeiro city ... more

C.R. Rainho; A.M.A. Velho; S.M. Corrêa; J.L. Mazzei; C.A.F. Aiub; I. Felzenszwalb
09/13/2013
Chromonephthea braziliensis; Mutagenicity; Secondary metabolites; Toxicity

Coral reefs are diverse ecosystems that have a high density of biodiversity leading to intense competition among species. These species may produce unknown substances, many with pharmacological value. Chromonephthea braziliensis is an invasive soft coral from the Indo-Pacific Ocean that is possibly transported by oil platforms and whose presence can be a threat to a region’s ... more

R.M. Carpes; B.G. Fleury; B.G. Lages; A.C. Pinto; C.A.F. Aiub; I. Felzenszwalb

Pages