Research Note

Related GMR Articles

06/18/2015
Gene; Intracranial aneurysm; Risk factor; SNP

Few studies have examined the genes related to risk fac­tors that may contribute to intracranial aneurysms (IAs). This study in Chinese patients aimed to explore the relationship between IA and 28 gene loci, proven to be associated with risk factors for IA. We recruited 119 patients with aneurysms and 257 controls. Single factor and logistic regression models were used to analyze the ... more

L.T. Zhang; F.J. Wei; Y. Zhao; Z. Zhang; W.T. Dong; Z.N. Jin; F. Gao; N.N. Gao; X.W. Cai; N.X. Li; W. Wei; F.S. Xiao; S.Y. Yue; J.N. Zhang; S.Y. Yang; W.D. Li; X.Y. Yang
03/31/2015
Ancestry informative markers; Association studies; Brazilian genetic admixture; Ethnicity; Population structure; SNP

Genetic association studies determine how genes influence traits. However, non-detected population substructure may bias the analysis, resulting in spurious results. One method to detect substructure is to genotype ancestry informative markers (AIMs) besides the candidate variants, quantifying how much ancestral populations contribute to the samples’ genetic background. The present study ... more

A.V.C. Coelho; R.R. Moura; C.A.J. Cavalcanti; R.L. Guimarães; P. Sandrin-Garcia; S. Crovella; L.A.C. Brandão

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