Research Article

Related GMR Articles

05/18/2015
Ankylosing spondylitis; Gene expression; Meta-analysis; Pathway analysis

The purpose of this study was to identify differentially expressed (DE) genes and biological processes associated with changes in gene expression in ankylosing spondylitis (AS). We performed a meta-analysis using the integrative meta-analysis of expression data program on publicly available microarray AS Gene Expression Omnibus (GEO) datasets. We performed Gene Ontology (GO) enrichment ... more

Y.H. Lee; G.G. Song
04/22/2015
Angiotensinogen; Gene polymorphism; Meta-analysis; Myocardial infarction

Numerous studies have evaluated the association between the T174M polymorphism in the angiotensinogen (AGT) gene and myocardial infarction (MI) risk. However, the specific association remains controversial because of small sample sizes and varied study designs among different studies. We performed a meta-analysis to assess this correlation. A comprehensive search was conducted to ... more

P.Y. Hu; Y.W. Wang; X.H. Pang; H.W. Wang
03/27/2015
Autism; Differentially expressed genes; Expression data; Meta-analysis; Microarray

The purpose of this study was to identify differentially expressed (DE) genes and biological processes associated with changes in gene expression in autism. We performed a meta-analysis using new publicly available Gene Expression Omnibus (GEO) datasets of autism. We performed Gene Ontology (GO) enrichment analyses and pathway analysis using the Kyoto Encyclopedia of Genes and Genomes ( ... more

L.F. Ning; Y.Q. Yu; E.T. GuoJi; C.G. Kou; Y.H. Wu; J.P. Shi; L.Z. Ai; Q. Yu
03/13/2015
C-erbB-2; Gastric cancer; Meta-analysis; Prognosis

The prognostic role of c-erbB-2 in gastric cancer is controversial. We conducted a meta-analysis to evaluate the relationship between c-erbB-2 expression and the prognosis of gastric cancer. We evaluated 20 published studies assessing the relationship between c-erbB-2 and gastric cancer prognosis. The Revman 5.0 software was used to perform literature retrieval, article selection, data ... more

Z.Q. Wang; B.J. Sun
02/06/2015
FABP2; Meta-analysis; Metabolic syndrome; Obesity; Type 2 diabetes mellitus

Previous studies have reported associations between the functional FABP2 Ala54Thr (rs1799883) polymorphism and type 2 diabetes mellitus (T2DM), obesity, and metabolic syndrome in different populations with conflicting results. We investigated the association between the FABP2 Ala54Thr polymorphism and T2DM (235 cases, 431 controls), obesity (377 cases, 431 controls), and ... more

Y. Liu; G. Wu; L. Han; K. Zhao; Y. Qu; A. Xu; Q. Huang
10/17/2013
Esophageal cancer; Flow cytometry; Gene transfection; MT-1E; MT-3; Proliferation

Metallothionein (MT)-3 has cell growth inhibitory activity, and is the only currently known MT subtype with unique physiological functions. The expression levels of MT-1E, a subtype of MT-1, were positively correlated with the degree of esophageal cancer malignancy. The present study aimed to investigate the effects of MT-3 and MT-1E gene transfection on the proliferation, cell cycle, and ... more

Z.Q. Tian; Y.Z. Xu; Y.F. Zhang; G.F. Ma; M. He; G.Y. Wang
09/26/2014
Esophageal cancer; Human microRNA-212; Prognostic factor

There have been few reports evaluating the expression and function of the microRNA miR-212 in esophageal cancer. The aim of this study was to investigate the relationship between miR-212 expression and clinicopathological factors and prognoses of esophageal cancer. MicroRNA was extracted from 46 esophageal cancer patients using the Taqman MicroRNA assay. All patients were at the same ... more

B. Qi; S.G. Liu; X.G. Qin; W.J. Yao; J.G. Lu; L. Guo; T.Y. Wang; H.C. Li; B.S. Zhao
07/25/2014
Esophageal cancer; MicroRNA-197; Prognosis

The aim of this study was to investigate the significance of the microRNA miR-197 expression level in relation to clinicopathological factors and prognoses of esophageal cancer (EC). MicroRNA was extracted using the Taqman® MicroRNA Assay from 46 EC patients at the same tumor node metastasis (TNM) stage, but with different prognoses, who underwent surgery. Paracancerous normal ... more

T.Y. Wang; S.G. Liu; B.S. Zhao; B. Qi; X.G. Qin; W.J. Yao
03/30/2015
Collateral circulation; Esophageal cancer; Nutrition; Plasma lipid; Thoracic duct

The aim of this study was to determine the influence of thoracic duct ligation on the lipid metabolism of patients with esophageal carcinoma after esophagectomy. A total of 74 patients with esophageal carcinoma who underwent esophagectomy were divided into 2 groups according to whether or not their thoracic duct was ligated. Thirty-nine patients were in the thoracic duct ligation group ... more

J.P. Liu; Y.H. Zhang; B. Yang; Q. Chen; L. Cao
12/03/2012
Bos indicus; Insulin-like growth factor; Polymorphisms; Yearling weight

Meat quality is an important trait for the beef industry. Backfat thickness, ribeye area, and shear force are traits measured late in life, and the investigation of molecular markers associated with these traits can help breeding programs. In cattle, some polymorphisms have been related to production traits. Thus, the purpose of this study was to assess the presence of polymorphisms in ... more

P.C. Tizioto; S.L. Meirelles; R.R. Tulio; A.N. Rosa; M.M. Alencar; S.R. Medeiros; F. Siqueira; G.L.D. Feijó; L.O.C. Silva; R.A.A.Torres Júnior; L.C.A. Regitano

Pages