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Toll-interleukin 1 receptor (TIR) domain containing adaptor protein (TIRAP; also known as MAL) is an essential adaptor molecule in Toll-like receptor signaling, involved in activating the innate immune response during infection. Genetic variations in the TIRAP gene may influence human susceptibility to infectious disease. To date, in the Chinese population, a possible ... more

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Innate immunity; Macaca thibetana; Phylogenetic analysis; TLR4 gene; Toll-like receptor

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Eriocheir sinensis; Na+-K+-ATPase; qRT-PCR; Salinity stress

Eriocheir sinensis is a euryhaline crab migrating from sea to freshwater habitats during the juvenile stage. We used quantitative real-time polymerase chain reaction (qRT-PCR) to investigate the gene expression profile of Na+-K+-ATPase, Hsp70 (heat shock protein 70) and Hsp90 in megalopa exposed to salinities of 0 ... more

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DDX6; Eriocheir sinensis; gametogenesis; oocyte growth

DDX6 belongs to a family of DEAD-box RNA helicases, which are RNA splicing proteins that ensure the correct folding and structure of mature RNA. Gametogenesis requires the participation of many kinds of RNA. To explore its functions during Eriocheir sinensis gametogenesis, we cloned a full-length DDX6 cDNA sequence from E. sinensis (Es-DDX6) which ... more

Q. Li; Y.L. Wang; J. Xie; W.J. Sun; M. Zhu; L. He; Q. Wang