Research Article

Related GMR Articles

08/06/2012
Genetic testing; Magnetic resonance imaging; Pelizaeus-Merzbacher disease; PLP1 gene; Prenatal diagnosis

Pelizaeus-Merzbacher disease (PMD) is a rare X-linked recessive disorder characterized by nystagmus, impaired motor development, ataxia, and progressive spasticity. Genetically defective or altered levels of proteolipid protein (PLP1) or gap-junction alpha protein 12 gene have been found to be a common cause. Here we report on two large Han Chinese families affected with this disease. The ... more

Y. Lv; L.H. Cao; H. Pang; L.N. Lu; J.L. Li; Y. Fu; S.L. Qi; Y. Luo; J. Li-Ling
12/12/2014
Clinical image; Hypertrophic cranial pachymeningitis; Magnetic resonance imaging; Pathological features

The objective of this study was to examine the clinical findings, magnetic resonance imaging (MRI), pathological features, and treatment experiments of patients with hypertrophic cranial pachymeningitis (HCP). The clinical findings, MRI, and pathological appearances of 9 patients with HCP were analyzed retrospectively. The thickened dura mater was markedly enhanced after contrast media ... more

C.H. Shi; S.T. Niu; Z.Q. Zhang
09/26/2014
Breast cancer; Genes; HER-2; Magnetic resonance imaging

The aim of this study was to investigate the correlation between apparent diffusion coefficients (ADCs), the relative apparent diffusion coefficient (rADC), and the pathological prognostic factor human epidermal growth factor receptor 2 (HER-2) in patients with breast cancer. A total of 64 women with breast cancer underwent breast diffusion-weighted imaging. HER-2 expression was detected ... more

X.Y. Jiang; Q.Z. Xie; X.S. Cao; T. Gao; C.Y. Xing; X.L. Li
04/08/2014
Cerebral small vessel disease; Magnetic resonance imaging; White matter lesion

White matter lesion (WML) in magnetic resonance imaging is commonly observed in patients with cerebral small vessel disease (SVD), but the pathological mechanism of WML in SVD is still unclear. We observed the metabolism and microscopic anatomy of white matter in SVD patients. Twelve subjects clinically diagnosed with SVD and 6 normal control subjects were examined with magnetic resonance ... more

L.A. Huang; X.Y. Ling; C. Li; S.J. Zhang; G.B. Chi; A.D. Xu
10/16/2015
Anterior cruciate ligament; Magnetic resonance imaging; Patellar tendon; Technical optimization

Ligament geometry is crucial to surgical treatment success in anterior cruciate ligament (ACL) injury. This study aimed to optimize the MRI technique to elucidate the geometry of the patellar ligament (PL) and ACL in vivo. A 1.5-T superconducting MRI system with a special surface coil and fast spin echo was used to acquire high-resolution T1-weighted images (H-T1WI) of the ACL. ... more

H.P. Wang; H.K. Cui; W. Yue; R.F. Yan; J.P. Ren; Z.S. Zhai; C.H. Liang; R.M. Yang; D.M. Han
03/27/2015
Chronic obstructive pulmonary disease; Computed tomography; Interstitial lung disease; Peripheral lung cancer; Spicule sign

The objective of this study was to investigate the correlation between spicular signs on computed tomography (CT) scans and peripheral lung cancer (PLC) that is associated with interstitial lung disease (ILD) and chronic obstructive pulmonary disease (COPD). We analyzed clinical data from 96 PLC cases and grouped patients based on whether they had interstitial pneumonia into either ILD/ ... more

L. Chen; L. Gao; W.L. Wu
03/06/2015
C-arm fluoroscopy; Computed tomography; Osteoporosis; Percutaneous kyphoplasty; Spine fractures; Spine neoplasms

This study aimed to evaluate the results and complications of image-guided percutaneous kyphoplasty (PKP) using computed tomography (CT) and C-arm fluoroscopy, with finger-touch guidance to determine the needle entry point. Of the 86 patients (106 PKP) examined, 56 were treated for osteoporotic vertebral compression fractures and 30 for vertebral tumors. All patients underwent image- ... more

G.Y. Wang; C.C. Zhang; K. Ren; P.P. Zhang; C.H. Liu; Z.A. Zheng; Y. Chen; R. Fang