Research Article

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04/17/2015
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H.B. Wang; W.G. Song; H.Q. Liu; F. Fang; Y. Xiao
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Chronic obstructive pulmonary disease; Polymorphism; Vitamin D-binding protein

Vitamin D-binding protein (DBP), a highly polymorphic serum protein, encoded by GC gene, is important in the development of chronic obstructive pulmonary disease (COPD). This meta-analysis was performed to assess the association between GC polymorphisms (1F, 1S, and 2 alleles) and COPD susceptibility. Published case-control studies were retrieved from the Pubmed, Embase, and China ... more

M. Xiao; T. Wang; T. Zhu; F. Wen
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Meta-analysis; Methylenetetrahydrofolate reductase; Polymorphism; Psoriasis

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J.H. Qi; N. Shi; Y.J. Chen; G. Nie
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Angiotensin-converting enzyme; Meta-analysis; Polymorphism; Sarcoidosis

Previous reports identified an association between sarcoidosis and an insertion/deletion (I/D) polymorphism in angiotensin-converting enzyme. Our meta-analysis of articles published between March 1996 and June 2013 identified studies in the PubMed, EMBASE, and the China National Knowledge Infrastructure databases. We examined whether angiotensin-converting enzyme polymorphisms influence ... more

R. Zhu; L.Q. Bi; H. Kong; S.L. Tilley; H. Wang; W.P. Xie
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Colorectal cancer; IGFBP-3; Meta-analysis; Meta-regression; Polymorphism

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J. Xu; L. Xu; L.T. Li; Q. You; L.S. Cha
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Coronary artery disease; Interleukin-6; Polymorphism

We conducted a case-control study to investigate the association between IL-6 -174 G>C and -572 C>G polymorphisms and the risk of coronary artery disease (CAD). We genotyped IL-6 ˗174 G>C and -572 C>G in 402 patients with CAD and 402 control individuals. IL-6 -174 G>C (rs1800795) and -572 C>G (rs1800796) alleles were detected by polymerase chain ... more

K. Wang; P.S. Dong; H.F. Zhang; Z.J. Li; X.M. Yang; H. Liu
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Hanwoo cattle; IGF1 concentration; Polymorphism

In this study, we investigated the associations between genetic variants in the promoter region of the insulin-like growth factor-1 (IGF1) gene and blood serum IGF1 concentration in Hanwoo cattle. Polymerase chain reaction primers were based on GenBank accession No. AF404761 and amplified approximately 533-bp segments. Newly identified sequences were submitted to GenBank ... more

H.Y. Chung; Y.J. Choi; H.N. Park; M.E. Davis
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Asthma; Meta-analysis; Polymorphism; Single nucleotide polymorphism

The IL-4R Q576R polymorphism has been reported to increase susceptibility to asthma, but the results are controversial. Thus, we performed a meta-analysis to evaluate the association of the IL-4R Q576R polymorphism and asthma risk in the Chinese Han population. A total of sixteen eligible case-control studies that evaluated the relationship between the IL-4R ... more

Z.Y. Huang; B.J. Cheng; G.J. Cai; B.F. Zhang
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ERCC1; ERCC2; Glioma; Polymorphism

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C.X. Zhou; J.H. Zhao
03/30/2015
Cardiovascular events; Hemodialysis; IL-6; Polymorphism

We aimed to investigate the role of IL-6 polymorphism on the development of cardiovascular events and coronary artery disease in patients receiving hemodialysis. Blood samples were collected from 216 patients receiving hemodialysis treatment. Polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) was used to genotype IL-6 -634C/G, -174G/C and -572C/G. By ... more

Y. Song; H.D. Gu; Y. He; J.W. Wang

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