Research Article

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03/06/2015
Chicken; Haplotype; HSP70; Single nucleotide polymorphism

This study was designed to detect the sequence variation of the chicken heat shock protein 70 (HSP70) gene. A total of 102 individuals from 8 native Chinese breeds together with Dwarf White Chicken and Red Junglefowl were used to detect sequence variations. The coding regions of the chicken HSP70 gene from 102 individuals were cloned and sequenced. Thirty-six variations ... more

J.K. Gan; L.Y. Jiang; L.N. Kong; X.Q. Zhang; Q.B. Luo
01/30/2015
Chinese population; CYP4F2 gene; Haplotype; Ischemic stroke; Single nucleotide polymorphism

The objective of this study was to explore the relationship between CYP4F2 gene polymorphism and ischemic stroke (IS) in the Han Chinese population. We performed a case-control study to genotype four single nucleotide polymorphisms (SNPs) (rs2108622, rs3093100, rs3093105, rs3093135) in the CYF4F2 gene. The genotype and haplotype distributions were compared between the ... more

H.Q. Yan; Y. Yuan; P. Zhang; Z. Huang; L. Chang; Y.K. Gui
12/04/2014
Hypoxia; Osteogenesis; Osteogenic differentiation; Periodontal ligament stem cells; Proliferation

Changes in oxygen concentration may influence various innate characteristics of stem cells. The effects of varying oxygen concentration on human periodontal ligament stem cells (HPDLSCs) has not been explored, particularly under hypoxia-related conditions. First, HPDLSCs were cultured from the periodontium of human teeth using the outgrowth method. STRO-1 and CD146 expression of HPDLSCs ... more

Q.B. Zhang; Z.Q. Zhang; S.L. Fang; Y.R. Liu; G. Jiang; K.F. Li
09/30/2004
Cancer; DmtDNA4977; In situ PCR; Kerns-Sayre syndrome deletion mutation; Mitochondria; Mitochondrial DNA; Real-time PCR

Levels of mtDNA4977 deletions (DmtDNA4977) have been found to be lower in tumors than in adjacent non-tumoral tissues. In 87 cancer patients, DmtDNA4977 was detected by multiplex polymerase chain reaction (PCR) amplification in 43 (49%) of the tumors and in 74 (85%) of the samples of non-tumoral tissues that ... more

M.Angela C. Dani; S.U. Dani; S.P.G. Lima; A. Martinez; B.M. Rossi; F. Soares; M.A. Zago; A.J.G. Simpson
05/09/2007
African Americans; American Caucasians; Brazilians; Mitochondrial DNA; Y-chromosome

We have previously shown evidence of strong sex-biased genetic blending in the founding and ongoing history of the Brazilian population, with the African and Amerindian contribution being highest from maternal lineages (as measured by mitochondrial DNA) and the European contribution foremost from paternal lineages (estimated from Y-chromosome haplogroups). The same phenomenon has been ... more

V.F. Gonçalves; F. Prosdocimi; L.S. Santos; J.M. Ortega; S.D.J. Pena
01/29/2007
Melipona mondury; Melipona rufiventris; Meliponini; Mitochondrial DNA; Polymorphic site; RFLP

Within the Meliponini, a widely distributed group of stingless bees, Melipona rufiventris has been considered as a single, cohesive species. Recently, analysis of morphological characters led to the splitting of this species into two species, M. mondury and M. rufiventris. The former occurs in the Atlantic Rain Forest ranging from Santa Catarina to Bahia ... more

G.S. Barni; R. Strapazzon; J.C.V. Guerra; G. Moretto
03/03/2009
allele-specific polymerase chain reaction; Bovine; maternal inheritance; Mitochondrial DNA

The Canchim (5/8 Charolais + 3/8 Zebu) beef cattle breed was developed at Southeast-Embrapa Cattle to take advantage of hybrid vigor and to combine the higher growth rate and beef quality of Charolais with tropical adaptations of Zebu. The development of three lineages (old, new, and crossbred) has increased its genetic basis. The genotypic origin (Bos taurus or Bos indicus) ... more

S.C. Méo; C.R. Ferreira; M.R. Chiaratti; F.V. Meirelles; L.C.A. Regitano; M.M. Alencar; P.F. Barbosa
12/16/2008
Conservation; Endangered species; Mitochondrial DNA; Oryx; Phylogenetic relationship

The present study reports the application of mitochondrial markers for the molecular phylogeny of Oryx species, including the Arabian oryx (AO), scimitar-horned oryx (SHO) and plains oryx (PO), using the Addax as an outgroup. Sequences of three molecular markers, 16S rRNA, cytochrome b and a control region, for the above four taxa were aligned and the topologies of respective ... more

H.A. Khan; I.A. Arif; A.A.Al Homaidan; A.H.Al Farhan
02/25/2009
Mitochondrial DNA; Polymorphism; Sea turtles; Single strand conformation polymorphism

Marine turtles are increasingly being threatened worldwide by anthropogenic activities. Better understanding of their life cycle, behavior and population structure is imperative for the design of adequate conservation strategies. The mtDNA control region is a fast-evolving matrilineal marker that has been employed in the study of marine turtle populations. We developed and tested a simple ... more

E.C. Reis; R.M. Albano; A.C.V. Bondioli; L.S. Soares; G. Lôbo-Hajdu; G. Lôbo-Hajdu
10/14/2008
A3243G mutation; Mitochondria; Mitochondrial disorders; Mitochondrial DNA; Transmitochondrial; Transmitochondrial mice

The mitochondrial A3243G tRNALeu(UUR) mutation associated with a variety of mitochondrial disorders results in a severe respiratory deficiency, an increase in reactive oxygen species (ROS) production and activities of anti-oxidative enzyme in vitro. However, the phenotypic implications of this mutation have not been described in vivo. Here, mitochondria carrying A3243G ... more

J. Li; K. Zhou; X. Meng; Q. Wu; S. Li; Y. Liu; J. Wang

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