Research Article

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02/02/2015

Association between SNPs in genes involved in folate metabolism and preterm birth risk

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We investigated the association between 12 single nucleotide polymorphisms (SNPs) in 11 genes involved in folate metabolic and preterm birth. A subset of SNPs selected from 11 genes/loci involved in the folic acid metabolism pathway were subjected to SNaPshot analysis in a case-control study. Twelve SNPs (CBS-C699T, DHFR-c594+59del19, GST01-C428T, MTHFD- ... more

B.J. Wang; M.J. Liu; Y. Wang; J.R. Dai; J.Y. Tao; S.N. Wang; N. Zhong; Y. Chen
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Chinese population; CYP4F2 gene; Haplotype; Ischemic stroke; Single nucleotide polymorphism

The objective of this study was to explore the relationship between CYP4F2 gene polymorphism and ischemic stroke (IS) in the Han Chinese population. We performed a case-control study to genotype four single nucleotide polymorphisms (SNPs) (rs2108622, rs3093100, rs3093105, rs3093135) in the CYF4F2 gene. The genotype and haplotype distributions were compared between the ... more

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