Related GMR Articles

13q deletion; Chromosomal microarray analysis; Complex phenotype; Fluorescence in situ hybridization; Karyotype; Ring chromosome 13

We describe the first postnatal diagnosis of a child from Central Brazil with de novo cytogenetic alterations in 13q showing malformations of the brain, eyes, distal limbs, and genitourinary tract, and severe intellectual disability. The karyotype was a constitutive 46,XX,r(13)[77]/45,XX,-13[17]/46,XX,idic r(13)[6]. Interphase and metaphase fluorescence in situ ... more

L.B. Minasi; I.P. Pinto; J.G. de Almeida; A.V. de Melo; D.M.C. Cunha; C.L. Ribeiro; G.P. Silva; M.G. Brasil; D.M. Silva; C.C. da Silva; A.D. da Cruz
C-banding; FISH; G-banding; Karyotype; Nucleolar organizer regions; Turtle
C.E.S. Zago
Acute promyelocytic leukemia; Cryptic insertions; Fluorescence in situ hybridization; promyelocytic leukemia/retinoic acid receptor alpha; Reverse transcription-polymerase chain reaction; Sequencing analysis

Acute promyelocytic leukemia (APL) is characterized by a reciprocal translocation, t(15;17)(q22;q11-21), resulting in the fusion of the promyelocytic leukemia (PML) and retinoic acid receptor alpha (RARα) genes. Using conventional cytogenetic methods, these translocations are normally detected in about 70-90% of patients; most negative results are due to technical problems or ... more

A. Choughule; S. Polampalli; P. Amre; S. Shinde; S. Banavali; K. Prabhash; R. Nair; P.G. Subramanian; S. Gujral; P.M. Parikh
Cynoglossus semilaevis; Fluorescence in situ hybridization; Major rDNA; Minor rDNA; Pleuronectiformes; Sex chromosome

Half-smooth tongue sole (Cynoglossus semilaevis) is an important aquaculture flatfish in China. Cytogenetic analysis has revealed that its sex determination system is female heterogametic (ZZ/ZW). The W chromosome is morphologically larger and has been considered evolutionarily younger than any other chromosome in the set. However, the genetic origin and evolution process of this ... more

L. Jiang; J. Jiang; J. Liu; J. Yuan; Y. Chen; Q. Zhang; X. Wang
Cross-amplification; Fluorescence in situ hybridization; Forage; Microsatellite

Aeschynomene falcata is an important forage species; however, because of low seed production, it is underutilized as forage species. Aeschynomene is a polyphyletic genus with a challenging taxonomic position. Two subgenera have been proposed, and it is suggested that Aeschynomene can be split in 2 genera. Thus, new markers, such as microsatellite sequences, are ... more

C.A. Polido; C.C. Mantello; A.P. Moraes; A.P. Souza; E.R. Forni-Martins
Fluorescence in situ hybridization; Freshwater fishes; Karyotype evolution; Molecular cytogenetics; Ribosomal DNA

In the present study, the karyotype and chromosomal characteristics of 9 species of the Bagridae fish family were investigated using conventional Giemsa staining as well as dual-color fluorescence in situ hybridization to detect the 18S and 5S rDNA sites. In addition to describing the karyotype of several Bagridae catfishes, we established molecular cytogenetic techniques to ... more

W. Supiwong; T. Liehr; M.B. Cioffi; A. Chaveerach; N. Kosyakova; X. Fan; T. Tanee; A. Tanomtong
Fluorescence in situ hybridization; Infertility; Reciprocal translocation; Sperm aneuploidy rates

A reciprocal translocation between the short arm of chromosome 1 and the long arm of chromosome 3 was observed in a pedigree of three carriers (proband, and his brother and mother). In this study, the three carriers had different clinical manifestations: the proband with infertility, his brother with spousal miscarriages, and his mother with no adverse reproductive history. Cytogenetic ... more

L.L. Li; Y. Dong; R.X. Wang; N. An; X. Yun; R.Z. Liu
C-banding; cytotaxonomy; Triatominae

Cytogenetic analyses of triatomines are considered to be important taxonomic tools. Thus, we analyzed the pattern of constitutive heterochromatin in 7 species of triatomine with fragmentation of the sex chromosome X, focusing on the cytotaxonomy of these triatomines. The species analyzed included Triatoma vitticeps, Triatoma melanocephala, Triatoma tibiamaculata ... more

A.L. Guerra; K.C.C. Alevi; J.A. Rosa; M.T.V. Azeredo-Oliveira
Ag-NORs; C-banding; Chromosomes; Karyotype evolution; Pericentric inversion

Hylidae is one of the most species-rich families of anurans, and 40% of representatives in this group occur in Brazil. In spite of such remarkable diversity, little is known about this family and its taxonomical and systematic features. Most hylids have 2n = 24, even though most of the cytogenetic data are mainly obtained based on the conventional chromosomal staining and are available ... more

M.A. Carvalho; M.T. Rodrigues; S. Siqueira; C. Garcia
C-banding; Chromosomal rearrangements; Cytotypes; Polymorphism

Bryconamericus comprises 56 species distributed into three groups, on the basis of the position and shape of the maxillary teeth: B. exodon, B. microcephalus and B. iheringii groups. Few cytogenetic data are available for this genus, but the diploid number of 52 chromosomes is quite common, although the karyotypic variability is extensive. This study aimed to ... more

L.L.L. da Silva; L. Giuliano-Caetano; A.L. Dias