Research Article

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Chitinases are important disease-related proteins that play critical roles in plant defense against disease. To investigate the function of chitinases in the resistance of Hami melon to Penicillium infection, the gene encoding chitinases, HmCHT-2, was cloned and RT-PCR was used to measure expression levels of HmCHT-2. When the Hami melon was infected by Penicillium sp after 0, 12, 36, 48, 60, ... more

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Tumor necrosis factor receptor-associated factor 6 (TRAF6) is a crucial adaptor molecule of the interleukin-1 receptor/Toll-like receptor (IL-1/TLR) superfamily, which can trigger downstream signaling cascades involved in innate immunity. The function of TRAF6 has been clarified in mammals but is poorly understood in chicken. In our study, we investigated TRAF6 function in birds, particularly ... more

J. Jin; J.S. Ran; C.W. Yang; X.S. Jiang; Y.G. Zhou; Z.Q. Feng; Y. Wang; D. Lan; P. Ren; Y.P. Liu
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Migration and invasion enhancer 1 (MIEN1) is a membrane-anchored protein that is highly expressed in various types of cancer, and is correlated with the PI3K/AKT pathway. The aim of this study was to investigate the expression of MIEN1 and its clinical pathological significance in breast cancer. We used immunohistochemical staining to examine the expression of MIEN1 in 40 samples of human ... more

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The mitochondrial calcium uptake 1 (MICU1) is a regulatory subunit of the mitochondrial calcium uniporter that plays an important role in calcium sensing. It contains two EF-hand domains that are well conserved across diverse species from protozoa to plants and metazoans. The loss of MICU1 function in mammals is attributed to several neurological disorders that involve movement dysfunction. ... more

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Fishes adapt to salinity changes primarily through osmotic pressure regulation, a process often associated with several genes, including 14-3-3a, NKCCla, A-14, and Na-K-ATPaseβ. The present study investigated the differential expression of genes 14-3-3a, NKCCla, A-14, and Na-K-ATPaseβ in the gill tissue of Mugil cephalus acclimated to low salinity. Susceptibility relationships between the four ... more

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Caco-2 Cells; Cell Line, Tumor; Colonic Neoplasms; Equilibrative Nucleoside Transporter 1; Equilibrative-Nucleoside Transporter 2; Gene expression; Gene Expression Regulation, Neoplastic; HCT116 Cells; Humans; Neoplasm Metastasis

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Amino acid sequence; Animals; Base Sequence; Chickens; Eimeria tenella; Escherichia coli; Gene expression; HSP70 Heat-Shock Proteins; Hydrophobic and Hydrophilic Interactions; Protozoan Proteins; Sequence Analysis, DNA

Members of the Eimeria genus are protozoan parasites of the subphylum Apicomplexa (Eimeriidae family), and belong to the coccidia group. Eimeria tenella is one of the most pathogenic species owing to its ability to penetrate the mucosa, and cause inflammation and damage. It is an obligate intracellular parasite that causes disease by destroying the host cells during multiplication. Heat shock ... more

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Tissue growth in most fishes occurs by muscular hyperplasia and hypertrophy, which are influenced by different regulatory factors, such as myostatin. The current study evaluated the influence of cultivation in hapas and earthen ponds on the diameter of white muscle fibers and on the myostatin (MSTN-1) gene in GIFT and Supreme varieties of tilapia. Fish of both varieties were reared for 204 ... more

E.C.S. Lima; J.A. Povh; R.A.A. Otonel; J.H. Leonhardt; A.A. Alfieri; S.A. Headley; F.P. Souza; A.R. Poveda-Parra; P.J. Furlan-Murari; N.M. Lopera-Barrero
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Animals; Aquaculture; Cichlids; Fish Proteins; Gene expression; Gene Expression Regulation, Developmental; Muscle, Skeletal; Myostatin; Ponds

Tissue growth in most fishes occurs by muscular hyperplasia and hypertrophy, which are influenced by different regulatory factors, such as myostatin. The current study evaluated the influence of cultivation in hapas and earthen ponds on the diameter of white muscle fibers and on the myostatin (MSTN-1) gene in GIFT and Supreme varieties of tilapia. Fish of both varieties were reared for 204 ... more

E.C.S. Lima; J.A. Povh; R.A.A. Otonel; J.H. Leonhardt; A.A. Alfieri; S.A. Headley; F.P. Souza; A.R. Poveda-Parra; P.J. Furlan-Murari; N.M. Lopera-Barrero

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