Research Article

Related GMR Articles

12/19/2012
cluster analysis; Cynodon dactylon; Genetic diversity; SSR

Fifty-five wild accessions of bermudagrass (Cynodon dactylon) were collected from southwest China (Sichuan, Chongqing, Yunnan, Guizhou, and Tibet), and their genetic diversity was analyzed using simple sequence repeat markers. A total of 267 polymorphic bands were detected with 18 primer combinations. The genetic similarity among the accessions ranged from 0.688 to 0.894 with an ... more

Y. Ling; X.Q. Zhang; X. Ma; S.Y. Chen; T.T. Chen; W. Liu
11/26/2015
Birds; Conservation; Grus japonensis; Population analysis

We isolated and characterized microsatellite loci for the red-crowned crane (Grus japonensis) from a microsatellite-enriched database, which was obtained using high-throughput sequencing technology. We designed primer sets for 445 microsatellite loci and after initial screening, 34 loci were genotyped in 31 red-crowned cranes. The number of observed alleles ranged from 3 to 10. ... more

L. Zhang; Z.H. Zhang; F.J. Shen; R. Hou; W.P. Zhang; Y.L. Liu; K.Y. Tu; A.L. Yang
09/25/2015
Coronary artery disease; IL-17A; IL-17F; Polymorphism

A case-control study was conducted to investigate the association between genetic variants of IL-17A rs2275913 and IL-17F rs763780 and the development of coronary artery disease (CAD) in a Chinese population. A total of 306 individuals with CAD and 306 unaffected individuals were enrolled from the Zhengzhou People’s Hospital between May 2012 and May 2014. The IL-17A ... more

G.Y. Geng; H.L. Liu; Y.J. Zhao; L. Wu; L. Mao; N. Ba
09/28/2015
DNA repair genes; Osteosarcoma; Overall survival; Polymorphism

We conducted a perspective study to investigate the role of ERCC1 (rs11615), ERCC2 (rs13181 and rs1799793), ERCC4 (rs1800067), and ERCC5 (rs17655) in NER pathway in the prognosis of osteosarcoma patients. In total, 146 osteosarcoma patients were recruited between 2008 and 2013. ERCC1 rs11615, ERCC2 rs13181 and rs1799793, ERCC4 rs1800067, and ERCC5 rs17655 gene polymorphisms were assessed ... more

M.J. Wang; Y. Zhu; X.J. Guo; Z.Z. Tian
09/22/2015
Chemotherapy; Clinical outcome; Glutathione S-transferases; Polymorphism

The aim of this study was to evaluate the role of GSTM1 null/present, GSTT1 null/present, and GSTP1 IIe105Val polymor­phisms in the clinical response to chemotherapy and treatment outcome of patients with breast cancer. A total of 262 subjects were randomly selected from among patients with a histologically confirmed breast cancer. The genotypes of GSTM1, ... more

J. Wang; T. Wang; G.Y. Yin; L. Yang; Z.G. Wang; X.B. Bu
09/22/2015
Cancer risk; Polymorphism; Renal cell carcinoma; Vascular endothelial growth factor

We conducted this case-control study to assess the role of the VEGF -2578C/A, +1612G/A, +936C/T and -634G/C gene polymorphisms in the development of renal cell carcinoma (RCC). A hospital-based case-control study was conducted in a 360 consecutive primary RCC patients and 360 age and gender-matched controls during January 2010 and January 2014. The polymerase chain reaction-restriction ... more

B.L. Shen; Q.S. Qu; S.Z. Miao; Y.X. Zhang
09/09/2015
broiler; Candidate gene; Polymorphism; Production trait; QTL

Genetic selection for production traits has resulted in a rapid improvement in animal performance and development. Previous studies have mapped quantitative trait loci for body weight at 35 and 41 days, and drum and thigh yield, onto chicken chromosome 4. We investigated this region for single nucleotide polymorphisms and their associations with important economic traits. Three positional ... more

F. Pértille; R. Zanella; A.M. Felício; M.C. Ledur; J.O. Peixoto; L.L. Coutinho
08/28/2015
Advanced non-small cell lung cancer; Clinical outcome; GSTP1; Polymorphism; XRCC1

We investigated the association between the polymorphisms GSTP1 rs1695 and XRCC1 rs1799782 and rs25487 and the clinical outcome of patients with non-small cell lung cancer (NSCLC) receiving cisplatin-based chemotherapy. Genotyping of GSTP1 rs1695 and XRCC1 rs1799782, and rs25487 was conducted by polymerase chain reaction-restriction fragment length ... more

J.Y. Liu; L.R. Li; Q.M. Liu
08/28/2015
Breast cancer; Glutathione S-transferases; Polymorphism

The current study aimed at evaluating the associa­tion between GSTM1 null/present, GSTT1 null/present, and GSTP1 IIe105Val polymorphisms and clinical response to chemotherapy and treatment outcome of breast cancers patients. Genotyping of GSTP1 rs1695, GSTT1 deletion, and GSTM1 deletion was performed by Polymerase Chain Reaction Restriction Fragment Length Polymor­phism (PCR-RFLP) assay. ... more

X. Wang; Z.H. Huang
08/21/2015
Clinical outcome; ERCC1; ERCC2; Osteosarcoma; Polymorphism

We aimed to evaluate the influence of four SNPs in ERCC1 and ERCC2 on the response to cisplatin-based treatment and on clinical outcome in patients with osteosarcoma. We identified 186 patients with osteosarcoma diagnosed between April 2009 and April 2011 who were eligible for inclusion in our study. Genotyping of ERCC1 rs11615, rs3212986, and rs2298881; and ... more

Z.H. Cao; H.P. Yin; N. Jiang; B. Yu

Pages