Research Article

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The goal of this study was to characterize the transcriptome of primary bovine mammalian epithelial cells (pBMECs) and to identify candidate genes for response and resistance to Staphylococcus aureus (strain S108), Escherichia coli (strain E23), and Klebsiella pneumoniae (strain K96) infection. Using Solexa sequencing, approximately 4.9 million total sequence tags ... more

L. Xiu; Y.B. Fu; Y. Deng; X.J. Shi; Z.Y. Bian; A. Ruhan; X. Wang
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Avian influenza virus; Chicken embryo fibroblast; H9N2; miRNA

There is limited information about microRNAs (miR­NAs) in H9N2 subtype influenza virus-infected chicken cells or tissues. In this study, 10,487,469 and 13,119,795 reads were obtained from in­fected and non-infected chicken embryo fibroblasts, respectively. Seven hundred and thirty-six and 1004 miRNAs, including mature miRNAs and precursors, were obtained from the infected and non-infected ... more

X. Peng; Q.S. Gao; L. Zhou; Z.H. Chen; S. Lu; H.J. Huang; C.Y. Zhan; M. Xiang
11/25/2015
Expression pattern; Flower bud; Male sterility; miRNA

MicroRNAs (miRNAs) are a class of non-coding endogenous negative regulators that regulate gene expression at both the transcriptional and post-transcriptional levels. However, little is known about the expression characteristics of miRNAs during pollen development in Brassica oleracea. In this study, five known and three novel miRNAs were identified and their expression patterns were ... more

J.H. Song; J. Yang; F. Pan; B. Jin
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Giant panda; Lactation; Mammary gland; miRNA

The giant panda (Ailuropoda melanoleuca) is one of the world’s most endangered mammals, and it has evolved several unusual biological and behavioral traits. During puberty, pregnancy, lactation, and involution, the mammary gland undergoes profound morphological and functional changes. A large number of microRNAs (miRNAs) have been identified to be involved in mammary gland ... more

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Breast cancer; ILIA; Insertion/deletion; miRNA; Polymorphism

The insertion/deletion polymorphism (rs3783553 TTCA/-) in the 3' untranslated region of interleukin-1A (IL1A) has been studied intensively and has been shown to affect tumor risk. We studied the frequency of the IL1A gene polymorphism rs3783553 and evaluated its relationship with breast cancer (BC). A hospital-based case-control study comprising 228 patients with histologically ... more

X. Huang; Y. Yang; Z.W. Cui; J. Wang; L.B. Gao; X. Huang; Y. Yang; Z.W. Cui; J. Wang; L.B. Gao
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DNA; miRNA; mRNA; Next-generation sequencing; Phalaenopsis; PhalDB

The orchid family Orchidaceae is one of the largest families of angiosperms; it includes approximately 35,000 species, displays a wide range of unique flower shapes and is a valued ornamental crop. Among the various species of orchids, the Phalaenopsis genus is the most widely commercialized among blooming potted plants. Our aim was to provide in-depth ... more

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Apoptosis; Gene; Glioblastoma; miRNA

Glioblastoma is considered incurable, even with a combination of therapies (chemo and radiotherapy), and surgical resection. New therapeutic approaches are needed to improve the prognosis of patients with glioblastoma. In recent decades, research has focused on molecular biology of brain tumors. We examined the role of programmed cell death, apoptosis, through two ... more

F. Pansani; L.P. Turra; F.S.Lizarte Neto; M.Lde A. Cirino; L.F. Tirapelli; F.M. Peria; C.G.Carlotti Junior; D.Pda C. Tirapelli
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Alcoholism; Apoptosis; blood; Cerebral ischemia; miRNA; morphology

One of the main global causes of mortality is cerebral ischemia. Studies report that alcohol abuse causes health problems, aggravating the conditions of neurological diseases. The role of microRNAs has been highlighted in the literature as biomarkers in various types of diseases, including neurological disorders. Evidence of dysregulation of serum miRNAs related to ... more

P.C. Novais; F.S.L. Neto; M.Lde A. Cirino; L.B. Porsani; J.P. da Silva; I.S. Gula; deT. Durand; C.A.M. de Carvalho; B.C. Schimming; deF.G.S. Tazima; C.G. Carlotti; B.O. Colli; D.Pda C. Tirapelli; L.F. Tirapelli
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Cytokine; Inflammatory; Regulatory; Systemic lupus erythematosus

To investigate the cytokine profile in serum and cerebrospinal fluid (CSF) from patients with systemic lupus erythematosus (SLE) and central nervous system infection, we measured interferon-g (IFN-g), interleukin-1b (IL-1b), IL-4, IL-6, IL-8, IL-10, and IL-17 levels in serum and CSF from 50 SLE patients and 38 matched controls. In patients with active compared to quiescent disease, serum ... more

Y. Yao; J.B. Wang; M.M. Xin; H. Li; B. Liu; L.L. Wang; L.Q. Wang; L. Zhao; Y. Yao; J.B. Wang; M.M. Xin; H. Li; B. Liu; L.L. Wang; L.Q. Wang; L. Zhao
05/06/2016
Bronchopulmonary dysplasia; Hyperoxia; Lung development; Transforming growth factor-b1

The aim of this study was to detect the expression of transforming growth factor-ß1 (TGF-ß1) in neonatal rats with hyperoxia-induced bronchopulmonary dysplasia (BPD) and to explore its relationship with lung development. Forty-eight rats (2-3 days old) were randomly divided into a hyperoxia group and a control group (N = 24) which were then fed in ≥95% oxygen atmosphere and air, ... more

B. Yan; W. Zhong; Q.M. He; S.Y. Zhang; J.K. Yu; Y.L. Pan; B. Yan; W. Zhong; Q.M. He; S.Y. Zhang; J.K. Yu; Y.L. Pan