Research Article

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Acute ischemic stroke; mRS score; NIHSS score; Thrombectomy; Thrombolysis

The number of stroke cases has more than doubled worldwide over the past four decades, including in low- and middle-income countries. Therefore, understanding the present situation of acute ischemic stroke in Vietnam is an urgent theme. The number of stroke cases in Vietnam is correlated with and reflected in the number of thrombolysis and thrombectomies performed ... more

N.H. Ngoc; N.V. Thong; N.Q. An
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Aging; Atrial fibrillation; Growth-associated protein (GAP43); Han nationality; Tyrosine hydroxylase; Xinjiang Uygur

The aim of this study was to explore the changes in gene and protein expressions of tyrosine hydroxylase (TH) and growth-associated protein 43 (GAP43) in aging atrial fibrillation patients of Xinjiang Uygur and Han nationality, and the significance of the changes. Real-time polymerase chain reaction and Western blot analysis were used to detect gene and protein expressions of TH and GAP43 ... more

Y.D. Li; J.X. Li; B.P. Tang; T.Y. Gan; G.J. Xu; X.H. Zhou; H. Li; X. Guo; A. Mahemuti; Q. Sun; Y.Y. Zhang; J. Wang
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Atorvastatin; Atrial fibrillation; Cardiology; Echocardiography; Left atrial function

The aim of this study was to evaluate the effects of atorvastatin on left atrial (LA) function in paroxysmal atrial fibrillation patients. Fifty-eight paroxysmal atrial fibrillation patients were divided into two groups (treatment and control groups). The echocardiography parameters, including LA active emptying volume (LAAEV), LA active emptying fraction, LA maximum volume, LA total ... more

Y.D. Li; B.P. Tang; F. Guo; J.X. Li; W. Han; Q. Tang; Y.Y. Zhang
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Atrial fibrillation; CETP; Polymerase chain reaction-restriction fragment length polymorphism; Polymorphism

The TaqI B polymorphism in the cholesterol ester transfer protein (CETP) (B1 and B2 alleles; rs708272) is associated with changes in enzyme activity and lipid concentrations. The B1 allele of the CETP gene is a known independent risk factor for genetic susceptibility to atrial fibrillation (AF); however, little is known about this polymorphism in the minority groups of Xinjiang, ... more

M. Bakeyi; M. Wulasihan; W.H. Lu; Y.C. Yang; J. Li; Z.Q. Liu; P.Y. He
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Atrial fibrillation; KCNE1; Meta-analysis; Polymorphism; susceptibility

KCNE1, a membrane protein that spans the membrane once is responsible for modulating potassium channel functions and plays an important role in the etiology of arrhythmia. Emerging evidence indicates that a common polymorphism (112G>A; rs1805127 G>A) in the KCNE1 gene contributes to atrial fibrillation (AF) risk; however, these studies showed inconclusive results. In this ... more

H.G. Han; H.S. Wang; Z. Yin; H. Jiang; M. Fang; J. Han
01/29/2014
Antithrombotic therapy; Atrial fibrillation; Elderly patients

This study aimed to analyze the impact factors and outcome of antithrombotic therapy in elderly patients over 65 years old that suffered from atrial fibrillation (AF). A total of 256 elderly patients with AF over 65 years old were divided into 3 groups: 65-74 years old (N = 86), 75-84 years old (N = 122), and over 85 years old (N = 48). The clinical characteristics, antithrombotic therapy ... more

W.Q. Gao; Y.T. Guo; J.L. Ma; P. Zhu; Y.T. Wang
12/07/2015
Atrial fibrillation; Gene polymorphism; KCNE1 (G38S); Uygur population

Current resources to support genetic screening among the Uygur population in Xinjiang territory for atrial fibrillation (AF) have not been well established and large-scale epidemiological analyses are needed. Using patients from the Xinjiang Uygur population as subjects, and the delayed rectifier potassium channel KCNE1 and its associated polymorphism G38S (rs1805127) as the candidate gene, we ... more

N. Wugeti; G. Yu-Jun; S. Juan; A. Mahemuti
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Atrial fibrillation; Connexin 40 (Cx40); Gene polymorphism; rs35594137

Atrial fibrillation (AF) occurrence has a known genetic component. Many reports have revealed a correlation between gene mutation and AF, involving genes related to ion channels, connexin (Cx), and those within the angiotensin system. In this study, the cor­relation between the Cx 40 polymorphism (rs35594137) and AF was investigated in patients with AF in the Xinjiang, Turpan, and Kashi ... more

Y. Feng; J. Sun; L. Wang; X.L. Hou
10/17/2016
Atrial fibrillation; Connexin 40; Gene polymorphism

We aimed to elucidate the association between connexin 40 (Cx40) genetic polymorphisms and atrial fibrillation (AF) in a Chinese population in Xinjiang comprising Uyghur and Han individuals. We enrolled 275 Uyghur and 305 age- and gender-matched Han subjects, and used polymerase chain reaction to detect single nucleotide polymorphisms (SNPs; -44G/A and +71A/G) in ... more

J. Hailati; Y.C. Yang; L. Zhang; P.Y. He; M. Baikeyi; W. Muhuyati; Z.Q. Liu
12/02/2015
Acute ischemic stroke; Complete blood count; Intercellular adhesion molecule-1; K469E; Mononuclear cells

Acute ischemic stroke (AIS) has become a serious health problem in many countries because of its poor outcome and worsening epidemic trend. Early identification of genetic risk factors and physiological indicators for stroke occurrence may help to reduce the incidence of stroke. Therefore, we conducted a case-control study including 50 AIS patients and 50 healthy individuals from a Chinese ... more

D. Wang; F.H. Zhang; Y.T. Zhao; X.G. Xiao; S. Liu; H.B. Shi; A.L. Lin; Y.J. Wang; Q. Han; Q.M. Sun

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