Research Article

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One of the main global causes of mortality is cerebral ischemia. Studies report that alcohol abuse causes health problems, aggravating the conditions of neurological diseases. The role of microRNAs has been highlighted in the literature as biomarkers in various types of diseases, including neurological disorders. Evidence of dysregulation of serum miRNAs related to ... more

P.C. Novais; F.S.L. Neto; M.Lde A. Cirino; L.B. Porsani; J.P. da Silva; I.S. Gula; deT. Durand; C.A.M. de Carvalho; B.C. Schimming; deF.G.S. Tazima; C.G. Carlotti; B.O. Colli; D.Pda C. Tirapelli; L.F. Tirapelli
Bassia indica; Cytology; DNA fingerprinting; morphology; RAPD-PCR; Weed

Bassia indica is a natural herb of medical and economic importance with a worldwide distribution, including in various regions of Egypt. It is primarily used for healing and is also considered a green fodder and can be used to remediate salty soils. We investigated morphological and germination parameters as well as the karyotype and genetic variation of ... more

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Abscission; Anatomy; Capsicum chinense; Flower; Fruit; morphology

The sweet and chili pepper species of the genus Capsicum are originally from America; however, currently they are grown worldwide. Although widely appreciated, especially in the Amazon region, there have been few studies about C. chinense. Characterization and classification studies can aid in pepper crop genetic breeding and development of new ... more

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Apoptosis; Cerebral ischemia; MicroRNA; Physical exercise

Stroke is a major public health problem, with high mortality rates, and a high frequency of disability. Between 1990 and 2010, stroke increased from the fifth to the third leading cause of disability. In addition, its incidence has increased among younger people, with severe health consequences and increased social costs. There is evidence that physical exercise ... more

L.B. Porsani; M.L.A. Cirino; F.S.Lizarte Neto; R.Z. Figueiredo; C.A.M. de Carvalho; J.P. da Silva; M.T. Durand; P.C. Novais; M.F.G.S. Tazima; C.G. Carlotti; B.O. Colli; D.P.C. Tirapelli; L.F. Tirapelli
Alcoholism; Atp5g3; Epigenetic; Expression; Mouse; Transcriptome

The mitochondrial ATP synthase, subunit c, isoform 3 gene (Atp5g3) encodes subunit 9, the subunit of the multisubunit enzyme that catalyzes ATP synthesis during oxidative phosphorylation in mitochondria. According to the Ensembl database, Atp5g3 in mice is located on chromosome 2 between 73746504 and 73749383 bp, within the genomic regions of two sets of quantitative ... more

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The morphological species concept is based on morpho­logical traits, which are often subject to subjectivity or artifact. Molecular evidence is needed to test the reliability of morphological classification of taxa that are controversial and to provide appropriate taxonomic de­limitation. In this study, we used 15 single-copy nuclear loci and 2 chlo­roplast fragments to verify the ... more

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Behavior; Biogeography; Chelonoidis; Cytochrome b; Hemoglobin; morphology

The discriminative potentials of biogeography, vocalization, morphology, cytogenetics, hemoglobin, and molecular profiling of cytochrome b as taxonomic techniques for differentiating Brazilian tortoises were evaluated in this study. In Brazil, two species of tortoises are described, Chelonoidis carbonarius and Chelonoidis denticulatus. However, in the present ... more

T.L. Silva; L.P.R. Venancio; C.R. Bonini-Domingos
Adhesion ability; Enterococcus faecalis; morphology; Viable but nonculturable

Enterococcus faecalis may enter a viable but nonculturable (VBNC) state under adverse conditions. E. faecalis, the major bacterial species present in failed root canal treatments, is thought to survive after endodontic treatment by entering a VBNC state. In this study, we characterized the VBNC state of E. faecalis. We designed 3 different protocols to successfully ... more

J. E; Y.T. Jiang; P.F. Yan; J.P. Liang
Cerebral ischemia; Inflammation; p38MAPK

Inflammation plays an important role in cerebral ischemia reperfusion, which can cause severe damage to the brain and may lead to cerebral hemorrhage transformation. p38-mitogen-activated protein kinase (p38mapk) has been implicated in the etiology of a number of diseases because it is a cause of inflammation, but comparatively little research has been carried out into its role in the ... more

Y.Q. Song; H.L. Zou; Y.J. Zhao; L.Q. Yu; Z.X. Tan; R. Kong; Y.Q. Song; H.L. Zou; Y.J. Zhao; L.Q. Yu; Z.X. Tan; R. Kong
Apoptosis; Caspase 3; Lipid-associated membrane proteins; Mycoplasma hyopneumoniae

Lipid-associated membrane proteins (LAMPs) are important in the pathogenicity of the Mycoplasma genus of bacteria. We investigated whether Mycoplasma hyopneumoniae LAMPs have pathogenic potential by inducing apoptosis in a St. Jude porcine lung epithelial cell line (SJPL). LAMPs from a pathogenic strain of M. hyopneumoniae (strain 232) were used in the research. Our ... more

B. Ni; F.F. Bai; Y. Wei; M.J. Liu; Z.X. Feng; Q.Y. Xiong; L.Z. Hua; G.Q. Shao