Research Article

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02/28/2013

Association of bovine Toll-like receptor 4 with tick infestation rates and blood histamine concentration

BMY cattle; Brahman; Histamine; Rhipicephalus microplus; Tick; TLR4 gene

We investigated a possible association between bovine Toll-like receptor 4 (TLR4) and resistance to tick infestation in 103 cattle, including BMY cattle (1/2 Brahman, 1/4 Murray Grey, and 1/4 Yunnan Yellow cattle), Brahman, and Red Angus grazing on improved pasture. The tick infestation weight and number of Rhipicephalus microplus and the blood histamine concentration ... more

G. Zhao; M. Yu; Q.W. Cui; X. Zhou; J.C. Zhang; H.X. Li; K.X. Qu; G.L. Wang; B.Z. Huang
07/17/2015

Protective effect and mechanism of probucol in the treatment of spinal cord injury

Inflammation; Oxidative stress; Probucol; Spinal cord injury

To investigate the effects of probucol on the treatment of spinal cord injury in rat, 80 rats were randomly divided into two groups of 40: a group treated with probucol and a control group. Allen’s method was used to establish a rat model of spinal cord injury. After establishment, probucol (500 mg·kg-1·day-1) was intraperitoneally injected into the treatment group ... more

W.B. Zhu; Y.H. Wang; G.F. Sun; J.H. Wu
12/22/2015

Lack of association between IL-10 -1082G/A polymorphism and chronic periodontal disease in adults

Inflammation; Interleukin-10; Periodontal disease; Polymorphism

Because of the complex interaction between periodontal pathogens and the host defense system, periodontitis is considered an inflammatory disorder of bacterial etiology that results in periodontal tissue damage. Genetic mechanisms may interfere with the gene expression of important inflammation mediators, modulating the immunologic response of an individual. In this study, we evaluated ... more

R. Hannum; F.R. Godoy; A.S. da Cruz; T.C. Vieira; L.B. Minasi; deM. e Silva; C.C. da Silva; A.D. da Cruz
12/14/2015

Effects of Danhong injection on hemodynamics and the inflammation-related NF-κB signaling pathway in patients with acute cerebral infarction

Acute cerebral infarction; Danhong injection; Hemodynamics; Inflammation

The objective of the current study was to investigate effects of Danhong injection on hemodynamics, inflammatory cytokines, and the NF-κB pathway in acute cerebral infarction. In total, 246 patients with acute cerebral infarction were divided into control (N = 121) and observation (N = 125) groups based on treatment. The control group underwent conventional treatment, while the ... more

Y. Jiang; Y.J. Lian
10/27/2015

Protective effect of lyophilized recombinant human brain natriuretic peptide on renal ischemia/reperfusion injury in mice

Brain natriuretic peptide; Hypoxia; Inflammation; Renal ischemia/reperfusion injury

Brain natriuretic peptide (BNP) has a protective effect on acute injury of the heart, brain, and lung. However, its role in acute kidney injury (AKI) remains unclear. The aim of this study was to investigate the effect of lyophilized recombinant human BNP (lrh-BNP) on AKI and the underlying molecular mechanisms. An experimental model for AKI was established using an ischemia/reperfusion ( ... more

X. Cao; H.Y. Xia; T. Zhang; L.C. Qi; B.Y. Zhang; R. Cui; X. Chen; Y.R. Zhao; X.Q. Li
02/05/2016

Correlation between adiponectin and hemorrhagic shock in mice

Adiponectin; Cytokines; Hemorrhagic shock; Inflammation; Mean arterial pressure; Serum

The aim of this study was to explore the relationship between adiponectin (ADPN) and hemorrhagic shock (HS) and the recovery after HS. This is significant for further understanding of the pathophysiological processes of HS and the development of better treatments. In total, 72 male C57BL/6 mice were assigned randomly to three groups: control, HS, and recovery (N = 24). The HS mouse model ... more

X. Gong; Y. Liu; S. Yao; J.F. Zheng; F. Wan; X.D. Xiang; X.P. Chai; X. Gong; Y. Liu; S. Yao; J.F. Zheng; F. Wan; X.D. Xiang; X.P. Chai
11/29/2017

Intestinal Dysbiosis Increases the Incidence of Malignant Melanoma in Mice Model

Immune; Inflammation; Melanoma; Microbial Dysbiosis; Probiotics
 Antibiotic-induced disruption of the intestinal microbiota
has serious consequences for human physiology. We conducted a
microbial dysbiosis animal model to study and directly provide evidence
for microbial dysbiosis contribution to malignant melanoma animal
model. Females C57BL/6 wild-type (WT) mice injected with a limiting
threshold ... more
X. Ren; X. Zhang; Y. Zhu; Y. Gamallat; A. Meyiah; S. Ma; Y. Xin