Research Article

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We evaluated the genetic association of growth traits [weight adjusted to 205 days of age (W205), 365 days of age (W365), and 550 days of age (W550); weight gain between 205 days of age and 365 days of age (WG1) and between 365 days of age and 550 days of age (WG2)] and reproductive traits [age at first calving (AFC); first calving interval (FCI)] with stayability in the herd (STAY), ... more

E.C.A. Rizzo; F.R.A. Neto; I.D.P.S. Diaz; M.M. Dias; R.B. Costa; H.T. Ventura; H.N. Oliveira; A.J.S. Falcão
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The UAS-Gal4 ectopic expression system is a widely used and highly valued tool that allows specific gene expression in Drosophila melanogaster. Yeast transcription factor Gal4 can be directed using D. melanogaster transcriptional control elements, and is often assumed to have little effect on the organism. By evaluation of the consequences of maternal and ... more

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Age at first calving; First calving interval; Genetic parameter; Longevity

The objective of the present study was to estimate genetic parameters for stayability at 60 months of age (STAY60) and its association with first lactation cumulative milk yield (P305), age at first calving (AFC), and first calving interval (FCI), in order to adopt these traits as selection criteria for longevity in Gir dairy cattle. Records for 2770 cows born between 1982 and 2008 from ... more

R.M.O. Silva; A.A. Boligon; A.R. Fernandes; A.E.Vercesi Filho; E. Faro; H. Tonhati; L.G. Albuquerque; A.B. Fraga; R.M.O. Silva; A.A. Boligon; A.R. Fernandes; A.E.Vercesi Filho; E. Faro; H. Tonhati; L.G. Albuquerque; A.B. Fraga
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In this study, we estimated the genetic parameters and identified the putative quantitative trait loci (QTL) associated with the length of productive life (LPL), days open (DO), and 305-day milk yield for the first lactation (FM305) of crossbred Holstein dairy cattle. Data comprising 4,739 records collected between 1986 and 2004 were used to estimate the variance-covariance components using ... more

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Genetics; GWAS; Hypertension; NPR3; Population diversity

Hypertension affects one-fifth of the world population. Genome-wide association studies (GWAS) have identified several single nucleotide polymorphisms (SNPs) that correlated with hyper­tension in large samples. However, the genetic mutations leading to hypertension might differ among various populations, as they have dif­ferent origins and are subjected to different environmental ... more

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Growth traits; GWAS; Jinghai yellow chicken; Linkage disequilibrium

Body weight is one of the most important economic traits in the poultry industry. In the present study, a custom SNP Beadchip was used to analyze the association between those 15 SNPs and 12 growth traits of Jinghai yellow chickens, and other important genetic parameters were also calculated and analyzed. The results indicated that nine of the 15 SNPs were associated with growth traits in ... more

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Genome-wide association study; GWAS; SLAF-seq; Yancheng chicken

Chicken (Gallus gallus) growth traits are important economic traits, and many studies have been conducted on genetic selection for body weight. However, most of these studies have detected functional chromosome mutations or regions by conventional molecular markers or gene chips. In this study, we performed a new genome-wide association study using specific-locus amplified ... more

C.F. Jin; Y.J. Chen; Z.Q. Yang; K. Shi; C.K. Chen
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Bos indicus; Early puberty; GWAS; U6 spliceosomal RNA

The aim of this study was to evaluate a genome wide association study (GWAS) approach to identify single nucleotide polymorphisms (SNPs) associated with fertility traits (early puberty) in Nellore cattle (Bos indicus). Fifty-five Nellore cows were selected from a herd monitored for early puberty onset (positive pregnancy at 18 months of age). Extremes of this phenotype were ... more

A.V. Nascimento; M.C. Matos; L.O. Seno; A.R.S. Romero; J.F. Garcia; A.B. Grisolia; A.V. Nascimento; M.C. Matos; L.O. Seno; A.R.S. Romero; J.F. Garcia; A.B. Grisolia
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Bos indicus; GWAS; Nelore; Quality carcass

Many studies have explored variability to select cattle with high genetic potential for economic interest traits. Genetic variability is a powerful tool to improve production indexes in cattle, as it also is associated with variations in meat and carcass quality traits. We made a Genome-Wide Association Study of beef cattle of Bos indicus origin, in ... more

M.E. Carvalho; F.S. Baldi; P.A. Alexandre; M.H.A. Santana; R.V. Ventura; R.S. Bueno; M.N. Bonin; F.M. Rezende; L.L. Coutinho; J.P. Eler; J.B.S. Ferraz
05/03/2019
Age at first calving; Calving interval; Costeño con Cuernos; Fertility; GWAS; Romosinuano

Inheritance of fertility traits in cattle is complex since they are controlled by multiple loci. Genome-wide association studies are an efficient tool to detect genomic regions that explain the phenotypic variation for a trait of interest. The aim of this study was to identify genomic regions that affect the age at first calving (AFC) and the calving ... more

J.C. Fernández; J.E. Pérez; N. Herrera; R. Martínez; D. Bejarano; J.F. Rocha