Research Article

Related GMR Articles

06/10/2015
Chicken; GRP78 gene; Heat stress; Quantitative real-time PCR; Single-nucleotide polymorphism

Glucose-regulated protein 78 (GRP78) is a molecular chaperone in the endoplasmic reticulum and can be induced by different kinds of environmental and physiological stress. Thus far, the role of the GRP78 gene in thermotolerance in chickens has not been investigated. In the present study, we detected sequence variations in the 5ꞌ-flanking region of the GRP78 gene and ... more

L.N. Kong; D.X. Zhang; C.L. Ji; X.Q. Zhang; Q.B. Luo
04/22/2015
Body measurement; Genetic variability; Silent information regulator 5; Single-nucleotide polymorphism; Ultrasound

Silent information regulator 5 (SIRT5), a member of the Sirtuin family class III nicotinamide adenine dinucleotide-dependent protein deacetylases, plays an important role in metabolic and aging processes in mammals. We identified 4 single-nucleotide polymorphisms (SNPs) (G22010A, G22052A, G22119T, and G22245C) in the 3' untranslated regions of the SIRT5 gene from 572 Qinchuan ... more

L.S. Gui; H.C. Wang; G.Y. Liu; L.S. Zan
04/15/2015
Male infertility; Methionine synthase; Methionine synthase reductase; Methylenetetrahydrofolate reductase; Single-nucleotide polymorphism

We examined the association between the methionine synthase reductase (MTRR A66G), methylenetetrahydrofolate reductase (MTHFR C677T and A1298C), and methionine synthase (MS A2756G) genotypes and non-obstructive male infertility in a Chinese population. This case-control study included 162 infertile Chinese patients with azoospermia (N = 100) or ... more

X.Y. Li; J.Z. Ye; X.P. Ding; X.H. Zhang; T.J. Ma; R. Zhong; H.Y. Ren
02/02/2015
Gestational diabetes; Macrophage migration inhibitory factor; Polymorphism; rs1007888; Single-nucleotide polymorphism

We investigated the association between macrophage migration inhibitory factor (MIF) rs1007888 single-nucleotide polymorphisms and the genetic susceptibility to gestational diabetes mellitus (GDM). A total of 240 GDM pregnant women (GDM group) and 330 healthy pregnant women (control group) were included in the study. Differences in the MIF rs1007888 genotype and allele ... more

Y. Zhan; C. Li; J. Chen; S. Yu; Q. Gao; Y.P. Wang; S.G. Liu

Pages