Research Article

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09/10/2015
Dinoprostone; mRNA; Prostaglandin receptors; Term pregnancy; Uterus

Prostaglandin E2 (dinoprostone) is largely used for labor induction. However, one-third of patients do not respond to treatment. One cause of this poor response may be associated with changes in regulation of prostaglandin E receptors (EP1-4). In this study, we investigated EP mRNA expression in the uterine cervix and lower uterine segment myometrium for term births. Biopsies were ... more

C.K. Konopka; W.G. Glanzner; M.L. Rigo; M.T. Rovani; F.V. Comim; P.B.D. Gonçalves; E.N. Morais; A.Q. Antoniazzi; C.F. Mello; I.B.M. Cruz
11/13/2015
Bronchial asthma; Children; Eosinophils; ECP; mRNA

Studies have shown that eosinophils are closely related to pathogenesis of bronchial asthma. Eosinophils release eosinophil cationic protein (ECP), which plays an important role in infection and allergic reactions. Serum ECP mRNA expression in children with bronchial asthma has not been adequately investigated. We analyzed serum ECP mRNA expression in 63 children with bronchial asthma and ... more

H.Y. Yu; X.Y. Li; Z.F. Cai; L. Li; X.Z. Shi; H.X. Song; X.J. Liu
05/09/2016
Arbovirus; Dengue; DGCR8; mRNA; RNAi

Dengue virus (DENV) and its four serotypes (DENV1-4) belong to the Flavivirus genus of the Flaviviridae family. DENV infection is a life-threatening disease, which results in up to 20,000 deaths each year. Viruses have been shown to encode trans-regulatory small RNAs, or microRNAs (miRNAs), which bind to messenger RNA and negatively regulate host or viral gene expression. During ... more

S.M.M. Casseb; D.B. Simith; K.F.L. Melo; M.H. Mendonça; A.C.M. Santos; V.L. Carvalho; A.C.R. Cruz; P.F.C. Vasconcelos; S.M.M. Casseb; D.B. Simith; K.F.L. Melo; M.H. Mendonça; A.C.M. Santos; V.L. Carvalho; A.C.R. Cruz; P.F.C. Vasconcelos
08/29/2023
Alcohol; Gene expression; Inflammatory response; mRNA; Protein; Therapeutic target

Alcohol dependence is a multifactorial inherited psychiatric disease that is difficult to diagnose and treat. Recent years have seen an increase in knowledge about molecular pathways and effect of proinflammatory cytokines on alcohol dependence. Understanding this pathology as an inflammatory condition opens the possibility of using new therapeutic agents to treat ... more

M. Rey; F.A. Aristizabal
07/14/2015
Acipenser schrenckii; Genetic diversity; Microsatellite; Next-generation sequencing; Polymorphism

Anthropogenic activities have seriously impacted wild resources of the Amur sturgeon, Acipenser schrenckii, and more infor­mation on local and regional population genetic structure is required to aid the conservation of this species. In this study, we report the develop­ment of 12 novel polymorphic microsatellite loci using next-generation sequencing technology, and the genotyping of ... more

L.M. Li; L. Wei; H.Y. Jiang; Y. Zhang; X.J. Zhang; L.H. Yuan; J.P. Chen
04/04/2016
Aquatic herb; Brasenia schreberi; Endangered species; Microsatellite marker; Next-generation sequencing

To understand genetic variability of the endangered aquatic herb Brasenia schreberi (Cabombaceae), we describe 31 microsatellite markers obtained using next-generation sequencing. A total of 24 individuals from the population of Jackson Lake, USA, were genotyped for each marker. Twenty-eight markers were polymorphic. The number of alleles per locus ranged from 1 to 9; the ... more

H. Liu; Z.C. Long; L.N. Li; Q.F. Wang; J.M. Chen; K. Liao; H. Liu; Z.C. Long; L.N. Li; Q.F. Wang; J.M. Chen; K. Liao; H. Liu; Z.C. Long; L.N. Li; Q.F. Wang; J.M. Chen; K. Liao
11/03/2016
Keratoconus; Mutation; Next-generation sequencing; VSX1

The aim of this study was to screen the visual system homeobox 1 (VSX1) gene in Turkish patients with keratoconus (KC). The patient group consisted of 44 patients who had undergone corneal transplant surgery before the age of 30, for advanced and rapidly progressive KC. The control group comprised 250 healthy individuals. We ... more

H. Bardak; M. Gunay; E. Yildiz; Y. Bardak; B. Gunay; H. Ozbas; O. Bagci
11/21/2016
Loci transferability; Microsatellite loci; Next-generation sequencing; Sillago japonica; Sillago sihama

Sillago sihama (Forsskål, 1775), a commercially important marine fishery species in the Indo-West Pacific, is being developed as a target species for aquaculture and stock enhancement in China. However, due to the limitations of traditional isolation methods, the available microsatellite loci, or simple sequence repeats (SSRs), of S. sihama lack ... more

R.X. Wu; H.R. Zhang; S.F. Niu; Y. Zhai; X.F. Liu; R.X. Wu; H.R. Zhang; S.F. Niu; Y. Zhai; X.F. Liu
12/29/2017
Martes flavigula; Microsatellite; Next-generation sequencing; Population genetics

The yellow-throated marten (Martes flavigula Boddaert 1785) is a medium-sized carnivore and a top predator in South Korea that is distributed throughout Western and Southeast Asia and Siberia in a wide range of habitats. In this study, we developed a panel of polymorphic microsatellite markers for M. flavigula by Illumina next-generation sequencing for ... more

M.Yeong Lee; H.Chang Moon; H.Sook Jeon; E.Geun Song; D. Woo; H.B. Park; T.Young Choi; K.Yeon Eo; Y. Hyun; K. Lee; Y.Seok Park; J.Young Moon; H.Jin Han; J. An
10/02/2015
Cotton; Disease; DNA; Fusarium; Mexicali valley

Cotton production in the Mexicali valley is adversely affected by wilt and root rot disease associated with Fusarium species. In the present study, we sought to isolate and identify the Fusarium species in the rhizosphere of transgenic insect-resistant cotton plants grown in the Mexicali valley. Our analyses isolated four native fungi from the rhizosphere of cotton ... more

T. Gonzalez-Soto; D. González-Mendoza; R. Troncoso-Rojas; A. Morales-Trejo; C. Cecena-Duran; A. Garcia-Lopez; O. Grimaldo-Juarez

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