Research Article

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11/22/2013
Microsatellite; Molecular markers; Polymorphism; Portunus trituberculatus

The Swimming crab Portunus trituberculatus (Portunidae) is an important economically food species. To provide molecular markers for P. trituberculatus, we isolated and characterized polymorphic microsatellite markers. We developed a 5'-anchored genomic library of P. trituberculatus DNA, and derived 45 positive clones. We designed 30 pairs of primers from the ... more

L.P. Ren; Y. Qin; X.C. Li; Y.N. Sun; R.X. Wang
11/22/2013
Fatty acid composition; Insertion/deletion mutation; Polymorphism; Simmental bulls; Snow Dragon black cattle; SREBP1 gene

The sterol regulatory element binding factor 1 gene (SREBP1) plays an important role in the biosynthesis of fatty acids and cholesterol, and in lipid metabolism. The objective of this study was to investigate the effect of genetic polymorphisms of SREBP1 on the fatty acid composition of muscle and carcass traits in Simmental bulls and Snow Dragon black cattle. The 84-bp ... more

L. Xu; L.P. Zhang; Z.R. Yuan; L.P. Guo; M. Zhu; X. Gao; H.J. Gao; J.Y. Li; S.Z. Xu
11/18/2013
Chemokine; Gene; Inflammation; OSCC; Polymorphism

We aimed to evaluate the effect of genetic variants of the chemokine C-C motif receptor (CCR5) in the pathogenesis of oral squamous cell carcinoma (OSCC). A total of 127 patients diagnosed with OSCC and 104 healthy individuals were included in the study. The polymorphisms CCR5 59029 and CCR5-delta32 were assessed with the polymerase chain reaction-restricted fragment length polymorphism ( ... more

C.R. Tanyel; Z.B. Cincin; B. Gokcen-Rohlig; K. Bektas-Kayhan; M. Unur; B. Cakmakoglu
11/18/2013
High-altitude adaptation; Hypoxia adaptation; Polymorphism; Vascular endothelial growth factor A (VEGF-A); Yak

Vascular endothelial growth factor-A gene (VEGF-A) is a key regulator of angiogenesis and an endothelial cell mitogen that plays an important role in high-altitude adaptation. In this study, we detected 2 novel single-nucleotide polymorphisms (SNPs) of VEGF-A by screening for genetic variation in 700 individuals of 3 domestic Chinese yak breeds - namely Gannan (GN), ... more

X.Y. Wu; C.N. Liang; X.Z. Ding; X. Guo; P.J. Bao; M. Chu; W.B. Liu; P. Yan
10/30/2013
Dactylopiidae; Genetic markers; Opuntia ficus indica; Polymorphism

The carmine cochineal Dactylopius opuntiae is a key pest in productive fields of forage cactus in Pernambuco, Brazil. Species identification by means of molecular markers assists in understanding the genetic profile, underpins morphological characterization, and supports the monitoring of populations in integrated management programs designed to control this pest. We evaluated ... more

D.M.P. Silva; A.Cdo E.S. Mergulhão; L.V. de Medeiros; M.V.B. Figueiredo; H.A. Burity
10/24/2013
Chronic obstructive pulmonary disease; Meta-analysis; Polymorphism; Tumor necrosis factor-alpha

Chronic obstructive pulmonary disease (COPD) is a chronic systemic inflammatory disease; increasing evidence indicates that the TNF-α polymorphism is associated with progression of this disease. Few studies have focused upon association between TNF-α -238G/A or -863C/A polymorphism and COPD risk. Reported associations have been controversial because of small sample size and varied study ... more

K. Cui; X.Y. Ge; H.L. Ma
10/18/2013
External apical root resorption; Interleukin-1β; Meta-analysis; Orthodontic; Polymorphism

The purpose of this meta-analysis was to determine whether genetic variants of the interleukin-1β[+3954 C>T (rs1143634)] (IL-1β +3954 C>T) gene polymorphisms were associated with orthodontic external apical root resorption (EARR). A meta-analysis was carried out using data entered into the PubMed and Embase electronic databases before October 5, 2012. A total of 7 studies were ... more

F.L. Wu; L.Y. Wang; Y.Q. Huang; W.B. Guo; C.D. Liu; S.G. Li
10/15/2013
EPHX1 gene; Esophageal cancer; Meta-analysis; Polymorphism

Epoxide hydrolases metabolize exogenous chemicals, including carcinogens such as polycyclic aromatic hydrocarbons. The relationship between microsomal epoxide hydrolase 1 (EPHX1) polymorphisms and esophageal cancer risk has been investigated in various ethnic populations, but the results have been contradictory. We investigated the association of EPHX1 Tyr113His and ... more

J.J. Hu; Z.T. Wang; B. Li
02/28/2013
Ossification; Polymorphism; Posterior longitudinal ligament; Transforming growth factor-β1

Ossification of the posterior longitudinal ligaments (OPLL) has been considered to be associated with abnormalities of bone metabolism, and transforming growth factor-β1 (TGF-β1) has been demonstrated to affect the bone remodeling process. We investigated two SNPs of the TGF-β1 promoter (-509C>T; rs1800469) and exon 1 (869T>C; rs1982073) in 298 Koreans (98 patients with OPLL and ... more

I.B. Han; A.E. Ropper; Y.J. Jeon; H.S. Park; D.A. Shin; Y.D. Teng; S.U. Kuh; N.K. Kim
10/18/2013
NPP1; Ossification; Polymorphism; Posterior longitudinal ligament; Postoperative progression

Ossification of the posterior longitudinal ligament (OPLL) is a condition of the spine that can cause paralysis by compressing the spinal cord. The aim of this study was to evaluate the possible role of nucleotide pyrophosphatase phosphodiesterase 1 gene (NPP1) polymorphism in the etiology and pathology of the OPLL in Chinese patients. DNA from patients with OPLL (N = 95) and ... more

Z. He; H. Zhu; L. Ding; H. Xiao; D. Chen; F. Xue

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