Research Article

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12/21/2012
Polymorphisms; Recurrent pregnancy loss; VEGF

Vascular endothelial growth factor (VEGF) regulates endothelial cell proliferation, migration and differentiation. VEGF plays a critical role in angiogenesis during placenta formation. We investigated whether VEGF gene polymorphisms are associated with recurrent pregnancy loss. Thirty-eight women with recurrent pregnancy loss and 30 control women with live-born children were recruited ... more

H. Şamlı; B.Ç. Demir; A. Özgöz; M.A. Atalay; G. Uncu
10/07/2014
Body measurement traits; Meat quality traits; Polymorphisms; Qinchuan cattle; Smoothened

Beef cattle breeding programs focus on improving important economic traits, including growth rates, and meat quantity and quality. Molecular marker-assisted selection based on genetic variation represents a potential method for breeding genetically improved livestock with better economic traits. Smoothened (SMO) protein is a signal transducer that contributes to the regulation of both ... more

Y.R. Zhang; Y.K. Li; C.Z. Fu; J.L. Wang; H.B. Wang; L.S. Zan
03/24/2014
DLK2 gene; Growth and meat traits; Mutation; Polymorphisms; Qinchuan cattle

The delta-like 2 homolog (DLK2) modulates adipogenesis, hematopoiesis, osteogenesis, and other cell-differentiation processes. In the present study, we detected potential polymorphisms in the DLK2 gene in 604 individuals of Qinchuan cattle by using PCR-RFLP and DNA-sequencing methods. Herein, we identified five novel single-nucleotide polymorphisms (SNPs) (g.888G>A, g.910A> ... more

N. Yang; L.S. Zan; Y.K. Li; J.B. Gao; X.H. Ma; C.Z. Fu; H. Wang; C. Adoligbe
02/28/2014
Asthma; IL-4; Meta-analysis; Polymorphisms; Promoter

This study aimed to more precisely assess the correlation between interleukin-4 (IL-4) promoter polymorphisms and the susceptibility risk of asthma. We conducted association studies on IL-4 promoter C-33T, C-589T, and G-1098T polymorphisms with asthma using data obtained from MEDLINE up to September 2011. Results showed that the polymorphisms IL-4 C-33T and C-589T were significantly ... more

L. Tang; H.G. Lin; B.F. Chen
06/12/2015
Molecular epidemiology; Osteoprotegerin; Polymorphisms; Rheumatoid arthritis

In order to investigate the association between osteoprotegerin (OPG) gene polymorphisms and rheumatoid arthritis (RA), we studied OPG rs3102735 T/C and rs2073618 G/C polymorphisms in a Chinese Han population comprising 574 patients with RA and 804 controls. Genotyping by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) was conducted. Our data ... more

X.H. Ye; J.L. Cheng; R.P. Liu
05/11/2015
Meat quality traits; Polymorphisms; Qinchuan cattle

Here, we detected 2 SNPs, A85C and T335C, that were located on the 3rd exon and the 3 untranslated regions of the bovine Osteocrin gene, respectively, using 413 Qinchuan cattle DNA samples. PCR-SSCP and DNA sequencing methods were specifically used. Three genotypes (AA, AC, and CC) were found at A85C; yet, only 2 genotypes (TC and CC) were found at T335C. Association analysis showed that ... more

Y.F. Huangfu; L.S. Zan; C. Adoligbe; H.B. Wang; H. Wang; J.B. Gao
03/31/2015
Amerindian; Ethnicity; Mexican Mestizo population; MMP-9; Polymorphisms; Population genetics

We studied the interethnic variation of the MMP-9 microsatellite in the Mestizo and Amerindian populations using blood samples collected from 435 healthy unrelated individuals from the Central Valley of Mexico. DNA samples were genotyped using the -90 (CA)12-27 repeat near the MMP transcriptional start site using capillary electrophoresis. Our data were ... more

R. Camacho-Mejorado; G. Noris; C. Santana; J.J. Magaña; A. Majluf-Cruz; J. Arellano-Galindo; A. De la Peña; J. Hernández-Juárez; E.S. Calderón-Aranda; M.A. Meraz-Ríos; R. Gómez
12/11/2007
Diversity; Ephedra; Ephedrine; Genetic distance; Molecular markers; Random amplified polymorphic DNA

Ephedra, also known as “ma huang”, is a dioecious, drought- and frost-resistant, perennial, evergreen shrub with compelling medicinal value. The genus is represented by 42 species around the world, 9 of which were provisionally reported from Pakistan. Species of the genus have a controversial taxonomy due to their overlapping morphological features. Conventional tools alone ... more

M.M. Shah; Z.A. Swati; S.H. Shah; A. Pervez; S. Ghafoor; H. Ahmad; U. Farooq
10/05/2007
Genetic variability; Pomacentridae; Pomacentrinae; Random amplified polymorphic DNA; Stegastes

The family Pomacentridae comprises about 326 species belonging to 28 genera. The genus Stegastes is composed of nearly 33 species, and 8 are endemic to the Brazilian Province, inhabiting the Brazilian coast (Stegastes fuscus, S. variabilis, S. leucosticus, S. uenfi, and S. pictus) or Western Atlantic oceanic islands (S. trindadensis ... more

E.A. Dias; A.S. Souza; W.F. Molina
12/08/2006
Bats; Chiroptera; Fluorescent in situ hybridization; Genetic variation; Random amplified polymorphic DNA

Random amplified polymorphic DNA molecular marker was utilized as a means of analyzing genetic variability in seven bat species: Molossus molossus, M. rufus, Eumops glaucinus, E. perotis, Myotis nigricans, Eptesicus furinalis, and Artibeus planirostris. The determination of genetic diversity was based on 741 bands produced by ... more

P.R.L. Moreira; E. Morielle-Versute

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