Research Article

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Myopalladin (MYPN) is a multifunctional protein that maintains sarcomeric integrity and regulates Z-line structure. It is an important candidate gene for meat quality selection through marker-assisted selection. Using PCR-RFLP technology, we discovered a single-nucleotide polymorphism (SNP) (A1795G in exon 9) of the MYPN gene. Allele frequencies of this SNP were investigated and evaluated ... more

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Beef cattle; Marker assisted selection; QTL; SNP; Zebu

We analyzed the polymorphisms TFAM HaeIII, TFAM MboI and FABP4 MspA1I in three Nellore lines selected for growth in order to evaluate how selection affects the frequencies of these polymorphisms and evaluate their association with growth and carcass traits in Zebu cattle. Birth, weaning and yearling weights, rump height, longissimus muscle area, backfat ... more

D.R. Ayres; F.R.P. Souza; M.E.Z. Mercadante; L.F.S. Fonseca; H. Tonhati; J.N.S.G. Cyrillo; S.F.M. Bonilha; L.G. Albuquerque
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ATP1A1 gene; Dairy cattle; Heat stress; K+-ATPase; Na+; SNP

Heat stress produces oxidative stress and affects the alternation of plasma K+ and Na+. Since Na+,K+-ATPase is sensitive to oxidative stress and critical for maintaining the homeostasis of these two ions, we examined the genetic polymorphism of the ATP1A1 gene in 160 Holstein cows using polymerase chain reaction low ionic strength ... more

Y.X. Liu; X. Zhou; D.Q. Li; Q.W. Cui; G.L. Wang
09/04/2013
Alpha-lactalbumin gene; Association analysis; Chinese Holstein cows; Milk production traits; SNP

The traits particularly important for milk production include milk yield, protein percentage, fat percentage, and the somatic cell score. Alpha-lactalbumin (α-LA) is an important whey protein of cow milk, and is also present in the milk of many other mammalian species. In this study, we analyzed the genetic polymorphisms of the α-LA gene and their relationship to milk production traits ( ... more

J.P. Zhou; C.H. Dong
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The perilipin (PLIN) gene is a candidate gene of carcass and fat traits in ducks. In order to study the molecular character of the PLIN gene and its function in different breeds of Chinese ducks, samples were obtained from the Chinese Academy of Agricultural Sciences Research Center for Birds, including 95 Peking ducks of the Z2 series, 91 Peking ducks of the Z4 series, ... more

H.L. Zhang; H.J. Fan; X.L. Liu; Y. Wu; S.S. Hou
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Allele; Gene; Jordan; MDR1; SNP

The multidrug resistance gene (MDR1 or ABCB1) codes for P-glycoprotein, which plays an important role in regulating absorption, distribution, and elimination of drugs. We examined MDR1 gene variants in 100 unrelated subjects from various regions of Jordan. The MDR1 gene was scanned using direct sequencing. Six rare variants in MDR1 were ... more

O.F. Khabour; K.H. Alzoubi; S.I. Al-Azzam; N.M. Mhaidat
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Cattle; CDIPT gene; PCR-RFLP; SNP; Ultrasound measurement traits

The CDIPT is crucial to the fatty acid metabolic pathway, intracellular signal transduction and energy metabolism in eukaryotic cells. We detected three SNPs at 3'-untranslated regions (UTR), named 3'-UTR_108 A > G, 3'-UTR_448 G > A and 3'-UTR_477 C > G, of the CDIPT gene in 618 Qinchuan cattle using PCR-RFLP and DNA sequencing methods. At each of the three SNPs, we ... more

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03/13/2013
Cattle; Hanwoo; Phospholipid transfer protein; Polymorphism; SNP

Phospholipid transfer protein (PLTP) regulates high-density lipoprotein metabolism. The gene encoding PLTP is located on bovine chromosome 13. The objective of this study was to identify single nucleotide polymorphisms (SNPs) in the Hanwoo (Bos taurus coreanae) PLTP gene to detect novel mutations affecting economically important traits. Five SNPs were identified in the coding ... more

J. Seong; J.D. Oh; H.K. Lee; G.J. Jeon; H.S. Kong
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Breeding; Fibroblast; Growth; QTL; SNP

In the past, the focus of broiler breeding programs on yield and carcass traits improvement led to problems related to meat quality. Awareness of public concern for quality resulted in inclusion of meat quality traits in the evaluation process. Nevertheless, few genes associated with meat quality attributes are known. Previous studies mapped quantitative trait loci for weight at 35 and 42 ... more

A.M. Felício; C. Boschiero; J.C.C. Balieiro; M.C. Ledur; J.B.S. Ferraz; A.S.A.M.T. Moura; L.L. Coutinho
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Makoei sheep; Myostatin gene; PCR; SNP; SSCP

Myostatin, a transforming growth factor-beta superfamily member, has been well documented as a negative regulator of muscle growth and development. Myostatin, which has 376 amino acids, is synthesized as a precursor protein. Polymorphism of the myostatin gene in Makoei sheep was investigated by PCR and single-strand conformation polymorphism technique (SSCP). Genomic DNA of 92 sheep was ... more

M. Farhadian; A. Hashemi; K. Mardani; R. Darvishzadeh; S. Jafari

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