Publications
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“Multiple variants of TERT and CLPTM1L constitute risk factors for lung adenocarcinoma”, vol. 11, pp. 370-378, 2012.
, Boezen HM (2009). Genome-wide association studies: what do they teach us about asthma and chronic obstructive pulmonary disease? Proc. Am. Thorac. Soc. 6: 701-703.
http://dx.doi.org/10.1513/pats.200907-058DP
PMid:20008879
Caporaso N, Gu F, Chatterjee N, Sheng-Chih J, et al. (2009). Genome-wide and candidate gene association study of cigarette smoking behaviors. PLoS One 4: e4653.
http://dx.doi.org/10.1371/journal.pone.0004653
PMid:19247474 PMCid:2644817
Chen WQ (2009). Estimation of cancer incidence and mortality in China in 2004-2005. Zhonghua Zhong. Liu Za Zhi. 31: 664-668.
PMid:20021861
Chung CC, Magalhaes WC, Gonzalez-Bosquet J and Chanock SJ (2010). Genome-wide association studies in cancer-current and future directions. Carcinogenesis 31: 111-120.
http://dx.doi.org/10.1093/carcin/bgp273
PMid:19906782 PMCid:2860704
Easton DF and Eeles RA (2008). Genome-wide association studies in cancer. Human Mol. Genet. 17: R109-115.
http://dx.doi.org/10.1093/hmg/ddn287
PMid:18852198
Fernandez-Garcia I, Ortiz-de-Solorzano C and Montuenga LM (2008). Telomeres and telomerase in lung cancer. J. Thorac. Oncol. 3: 1085-1088.
http://dx.doi.org/10.1097/JTO.0b013e3181886713
PMid:18827602
Gu D, Kelly TN, Wu X, Chen J, et al. (2009). Mortality attributable to smoking in China. N. Engl. J. Med. 360: 150-159.
http://dx.doi.org/10.1056/NEJMsa0802902
PMid:19129528
Helland A and Brustugun OT (2009). Lung cancer in smokers and never-smokers. Tidsskr. Nor. Laegeforen. 129: 1859-1862.
http://dx.doi.org/10.4045/tidsskr.08.0652
PMid:19844277
Hsiung CA, Lan Q, Hong YC, Chen CJ, et al. (2010). The 5p15.33 locus is associated with risk of lung adenocarcinoma in never-smoking females in Asia. PLoS Genet. 6.
Jin G, Xu L, Shu Y, Tian T, et al. (2009). Common genetic variants on 5p15.33 contribute to risk of lung adenocarcinoma in a Chinese population. Carcinogenesis 30: 987-990.
http://dx.doi.org/10.1093/carcin/bgp090
PMid:19369581
Kang JU, Koo SH, Kwon KC, Park JW, et al. (2008). Gain at chromosomal region 5p15.33, containing TERT, is the most frequent genetic event in early stages of non-small cell lung cancer. Cancer Genet. Cytogenet. 182: 1-11.
http://dx.doi.org/10.1016/j.cancergencyto.2007.12.004
Landi MT, Chatterjee N, Yu K, Goldin LR, et al. (2009). A genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinoma. Am. J. Hum. Genet. 85: 679-691.
http://dx.doi.org/10.1016/j.ajhg.2009.09.012
PMid:19836008 PMCid:2775843
Maser RS, Choudhury B, Campbell PJ, Feng B, et al. (2007). Chromosomally unstable mouse tumours have genomic alterations similar to diverse human cancers. Nature 447: 966-971.
http://dx.doi.org/10.1038/nature05886
PMid:17515920 PMCid:2714968
McKay JD, Hung RJ, Gaborieau V, Boffetta P, et al. (2008). Lung cancer susceptibility locus at 5p15.33. Nat. Genet. 40: 1404-1406.
http://dx.doi.org/10.1038/ng.254
PMid:18978790 PMCid:2748187
Metzger R, Vallbohmer D, Muller-Tidow C, Higashi H, et al. (2009). Increased human telomerase reverse transcriptase (hTERT) mRNA expression but not telomerase activity is related to survival in curatively resected non-small cell lung cancer. Anticancer Res. 29: 1157-1162.
PMid:19414359
Molina JR, Yang P, Cassivi SD, Schild SE, et al. (2008). Non-small cell lung cancer: epidemiology, risk factors, treatment, and survivorship. Mayo Clin. Proc. 83: 584-594.
PMid:18452692 PMCid:2718421
Nishio Y, Nakanishi K, Ozeki Y, Jiang SX, et al. (2007). Telomere length, telomerase activity, and expressions of human telomerase mRNA component (hTERC) and human telomerase reverse transcriptase (hTERT) mRNA in pulmonary neuroendocrine tumors. Jpn. J. Clin. Oncol. 37: 16-22.
http://dx.doi.org/10.1093/jjco/hyl118
PMid:17060405
Perera SA, Maser RS, Xia H, McNamara K, et al. (2008). Telomere dysfunction promotes genome instability and metastatic potential in a K-ras p53 mouse model of lung cancer. Carcinogenesis 29: 747-753.
http://dx.doi.org/10.1093/carcin/bgn050
PMid:18283039
Rafnar T, Sulem P, Stacey SN, Geller F, et al. (2009). Sequence variants at the TERT-CLPTM1L locus associate with many cancer types. Nat. Genet. 41: 221-227.
http://dx.doi.org/10.1038/ng.296
PMid:19151717
Reguart N, Cardona AF, Carrasco E, Gomez P, et al. (2008). BRCA1: a new genomic marker for non-small-cell lung cancer. Clin. Lung Cancer 9: 331-339.
http://dx.doi.org/10.3816/CLC.2008.n.048
PMid:19073515
Sreeja L, Syamala V, Raveendran PB, Santhi S, et al. (2008). p53 Arg72Pro polymorphism predicts survival outcome in lung cancer patients in Indian population. Cancer Invest. 26: 41-46.
http://dx.doi.org/10.1080/07357900701638459
PMid:18181044
Stinchcombe TE and Socinski MA (2009). Current treatments for advanced stage non-small cell lung cancer. Proc. Am. Thorac. Soc. 6: 233-241.
http://dx.doi.org/10.1513/pats.200809-110LC
PMid:19349493
Strazisar M, Mlakar V, Rott T and Glavac D (2009). Somatic alterations of the serine/threonine kinase LKB1 gene in squamous cell (SCC) and large cell (LCC) lung carcinoma. Cancer Invest. 27: 407-416.
http://dx.doi.org/10.1080/07357900802427919
PMid:19229701
Sun Y (1987). The epidemiology, etiology and carcinogenesis of lung cancer. Beijing Med. 10: 56.
Svejgaard A, Hauge M, Jersild C, Platz P, et al. (1975). The HLA system. An introductory survey. Monogr. Hum. Genet. 7: 1-100.
PMid:55961
Thomas G, Jacobs KB, Yeager M, Kraft P, et al. (2008). Multiple loci identified in a genome-wide association study of prostate cancer. Nat. Genet. 40: 310-315.
http://dx.doi.org/10.1038/ng.91
PMid:18264096
Wang Y, Broderick P, Webb E, Wu X, et al. (2008). Common 5p15.33 and 6p21.33 variants influence lung cancer risk. Nat. Genet. 40: 1407-1409.
http://dx.doi.org/10.1038/ng.273
PMid:18978787 PMCid:2695928
Wang Y, Broderick P, Matakidou A, Eisen T, et al. (2010). Role of 5p15.33 (TERT-CLPTM1L), 6p21.33 and 15q25.1 (CHRNA5-CHRNA3) variation and lung cancer risk in never-smokers. Carcinogenesis 31: 234-238.
http://dx.doi.org/10.1093/carcin/bgp287
PMid:19955392
Yamamoto K, Okamoto A, Isonishi S, Ochiai K, et al. (2001). A novel gene, CRR9, which was up-regulated in CDDP-resistant ovarian tumor cell line, was associated with apoptosis. Biochem. Biophys. Res. Commun. 280: 1148-1154.
http://dx.doi.org/10.1006/bbrc.2001.4250
PMid:11162647
Yamamoto Y, Chochi Y, Matsuyama H, Eguchi S, et al. (2007). Gain of 5p15.33 is associated with progression of bladder cancer. Oncology 72: 132-138.
http://dx.doi.org/10.1159/000111132
PMid:18025801
Zhu CQ, Cutz JC, Liu N, Lau D, et al. (2006). Amplification of telomerase (hTERT) gene is a poor prognostic marker in non-small-cell lung cancer. Br. J. Cancer 94: 1452-1459.
http://dx.doi.org/10.1038/sj.bjc.6603110
PMid:16641908 PMCid:2361293
Zienolddiny S, Skaug V, Landvik NE, Ryberg D, et al. (2009). The TERT-CLPTM1L lung cancer susceptibility variant associates with higher DNA adduct formation in the lung. Carcinogenesis 30: 1368-1371.
http://dx.doi.org/10.1093/carcin/bgp131
PMid:19465454