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2012
H. C. Loh, Tang, P. Y., Tee, S. F., Chow, T. J., Cheah, Y. C., and Singh, S. S. J., BDNF and DARPP-32 genes are not risk factors for schizophrenia in the Malay population, vol. 11, pp. 725-730, 2012.
Albert KA, Hemmings HC Jr, Adamo AI, Potkin SG, et al. (2002). Evidence for decreased DARPP-32 in the prefrontal cortex of patients with schizophrenia. Arch. Gen. Psychiatry 59: 705-712. http://dx.doi.org/10.1001/archpsyc.59.8.705 PMid:12150646 Angelucci F, Brene S and Mathe AA (2005). BDNF in schizophrenia, depression and corresponding animal models. Mol. Psychiatry 10: 345-352. http://dx.doi.org/10.1038/sj.mp.4001637 PMid:15655562 Chen ZY, Jing D, Bath KG, Ieraci A, et al. (2006). Genetic variant BDNF (Val66Met) polymorphism alters anxiety-related behavior. Science 314: 140-143. http://dx.doi.org/10.1126/science.1129663 PMid:17023662    PMCid:1880880 Egan MF, Weinberger DR and Lu B (2003). Schizophrenia, III: brain-derived neurotropic factor and genetic risk. Am. J. Psychiatry 160: 1242. http://dx.doi.org/10.1176/appi.ajp.160.7.1242 PMid:12832235 Fienberg AA, Hiroi N, Mermelstein PG, Song W, et al. (1998). DARPP-32: regulator of the efficacy of dopaminergic neurotransmission. Science 281: 838-842. http://dx.doi.org/10.1126/science.281.5378.838 PMid:9694658 Gratacòs M, González JR, Mercader JM, de Cid R, et al. (2007). Brain-derived neurotrophic factor Val66Met and psychiatric disorders: meta-analysis of case-control studies confirm association to substance-related disorders, eating disorders, and schizophrenia. Biol. Psychiatry 61: 911-922. http://dx.doi.org/10.1016/j.biopsych.2006.08.025 PMid:17217930 Hong CJ, Yu YW, Lin CH and Tsai SJ (2003). An association study of a brain-derived neurotrophic factor Val66Met polymorphism and clozapine response of schizophrenic patients. Neurosci. Lett. 349: 206-208. http://dx.doi.org/10.1016/S0304-3940(03)00828-0 Jonsson EG, Edman-Ahlbom B, Sillen A, Gunnar A, et al. (2006). Brain-derived neurotrophic factor gene (BDNF) variants and schizophrenia: an association study. Prog. Neuropsychopharmacol. Biol. Psychiatry 30: 924-933. http://dx.doi.org/10.1016/j.pnpbp.2006.02.008 PMid:16581172 Kanazawa T, Glatt SJ, Kia-Keating B, Yoneda H, et al. (2007). Meta-analysis reveals no association of the Val66Met polymorphism of brain-derived neurotrophic factor with either schizophrenia or bipolar disorder. Psychiatry Genet. 17: 165-170. http://dx.doi.org/10.1097/YPG.0b013e32801da2e2 PMid:17417060 Li CH, Liao HM, Hung TW and Chen CH (2006). Mutation analysis of DARPP-32 as a candidate gene for schizophrenia. Schizophr. Res. 87: 1-5. http://dx.doi.org/10.1016/j.schres.2006.04.003 PMid:16750903 Meyer-Lindenberg A, Straub RE, Lipska BK, Verchinski BA, et al. (2007). Genetic evidence implicating DARPP-32 in human frontostriatal structure, function, and cognition. J. Clin. Invest. 117: 672-682. http://dx.doi.org/10.1172/JCI30413 PMid:17290303    PMCid:1784004 Muglia P, Vicente AM, Verga M, King N, et al. (2003). Association between the BDNF gene and schizophrenia. Mol. Psychiatry 8: 146-147. http://dx.doi.org/10.1038/sj.mp.4001221 PMid:12610646 Murray RM, Sham P, van Os J, Zanelli J, et al. (2004). A developmental model for similarities and dissimilarities between schizophrenia and bipolar disorder. Schizophr. Res. 71: 405-416. http://dx.doi.org/10.1016/j.schres.2004.03.002 PMid:15474912 Nanko S, Kunugi H, Hirasawa H, Kato N, et al. (2003). Brain-derived neurotrophic factor gene and schizophrenia: polymorphism screening and association analysis. Schizophr. Res. 62: 281-283. http://dx.doi.org/10.1016/S0920-9964(02)00349-3 Neves-Pereira M, Cheung JK, Pasdar A, Zhang F, et al. (2005). BDNF gene is a risk factor for schizophrenia in a Scottish population. Mol. Psychiatry 10: 208-212. http://dx.doi.org/10.1038/sj.mp.4001575 PMid:15630410 Nishi A, Watanabe Y, Higashi H, Tanaka M, et al. (2005). Glutamate regulation of DARPP-32 phosphorylation in neostriatal neurons involves activation of multiple signaling cascades. Proc. Natl. Acad. Sci. U. S. A. 102: 1199-1204. http://dx.doi.org/10.1073/pnas.0409138102 PMid:15657149    PMCid:545831 Qian L, Zhao J, Shi Y, Zhao X, et al. (2007). Brain-derived neurotrophic factor and risk of schizophrenia: an association study and meta-analysis. Biochem. Biophys. Res. Commun. 353: 738-743. http://dx.doi.org/10.1016/j.bbrc.2006.12.121 PMid:17196936 Sheehan DV, Lecrubier Y, Sheehan KH, Amorim P, et al. (1998). The Mini-International Neuropsychiatric Interview (M.I.N.I.): the development and validation of a structured diagnostic psychiatric interview for DSM-IV and ICD-10. J. Clin. Psychiatry 59 (Suppl 20): 22-33. Skibinska M, Hauser J, Czerski PM, Leszczynska-Rodziewicz A, et al. (2004). Association analysis of brain-derived neurotrophic factor (BDNF) gene Val66Met polymorphism in schizophrenia and bipolar affective disorder. World J. Biol. Psychiatry 5: 215-220. http://dx.doi.org/10.1080/15622970410029936 PMid:15543516 Squassina A, Piccardi P, Del Zompo M, Rossi A, et al. (2010). NRG1 and BDNF genes in schizophrenia: an association study in an Italian case-control sample. Psychiatry Res. 176: 82-84. http://dx.doi.org/10.1016/j.psychres.2009.03.017 PMid:20061032 Svenningsson P, Tzavara ET, Liu F, Fienberg AA, et al. (2002a). DARPP-32 mediates serotonergic neurotransmission in the forebrain. Proc. Natl. Acad. Sci. U. S. A. 99: 3188-3193. http://dx.doi.org/10.1073/pnas.052712699 PMid:11880652    PMCid:122494 Svenningsson P, Tzavara ET, Witkin JM, Fienberg AA, et al. (2002b). Involvement of striatal and extrastriatal DARPP-32 in biochemical and behavioral effects of fluoxetine (Prozac). Proc. Natl. Acad. Sci. U. S. A. 99: 3182-3187. http://dx.doi.org/10.1073/pnas.052712799 PMid:11880651    PMCid:122493 Takahashi T, Suzuki M, Tsunoda M, Kawamura Y, et al. (2007). Association between the brain-derived neurotrophic factor Val66Met polymorphism and brain morphology in a Japanese sample of schizophrenia and healthy comparisons. Neurosci. Lett. 435: 34-39. http://dx.doi.org/10.1016/j.neulet.2008.02.004 PMid:18325670 Tee SF, Chow TJ, Tang PY and Loh HC (2010). Linkage of schizophrenia with TPH2 and 5-HTR2A gene polymorphisms in the Malay population. Genet. Mol. Res. 9: 1274-1278. http://dx.doi.org/10.4238/vol9-3gmr789 PMid:20623453 Tee SF, Tang PY and Loh HC (2011). No evidence for association between DRD3 and COMT with schizophrenia in a Malay population. Genet. Mol. Res. 10: 1850-1855. http://dx.doi.org/10.4238/vol10-3gmr1237 PMid:21948748 Tee SF, Tang PY and Loh HC (2012). COMT haplotype analyses in Malaysian with schizophrenia. Psychiatry Res. 195: 83-84. http://dx.doi.org/10.1016/j.psychres.2011.07.039 PMid:21872942 Xu MQ, St Clair D, Ott J, Feng GY, et al. (2007). Brain-derived neurotrophic factor gene C-270T and Val66Met functional polymorphisms and risk of schizophrenia: a moderate-scale population-based study and meta-analysis. Schizophr. Res. 91: 6-13. http://dx.doi.org/10.1016/j.schres.2006.12.008 PMid:17289348
2011
S. F. Tee, Tang, P. Y., and Loh, H. C., No evidence for association between DRD3 and COMT with schizophrenia in a Malay population, vol. 10, pp. 1850-1855, 2011.
Chang HA, Lu RB, Lin WW, Chang CC, et al. (2007). Lack of association between dopamine D3 receptor Ser9Gly polymorphism and schizophrenia in Han Chinese population. Acta Neuropsychiatr. 19: 344-350. http://dx.doi.org/10.1111/j.1601-5215.2007.00214.x Chen J, Lipska BK, Halim N, Ma QD, et al. (2004). Functional analysis of genetic variation in catechol-o-methyltransferase (COMT): effects on mRNA, protein, and enzyme activity in postmortem human brain. Am. J. Hum. Genet. 75: 807-821. http://dx.doi.org/10.1086/425589 PMid:15457404 Crocq MA, Mant R, Asherson P, Williams J, et al. (1992). Association between schizophrenia and homozygosity at the dopamine D3 receptor gene. J. Med. Genet. 29: 858-860. http://dx.doi.org/10.1136/jmg.29.12.858 PMid:1362221    PMCid:1016201 De Luca V, Tharmalingam S, Müller DJ, Wong G, et al. (2006). Gene-gene interaction between MAOA and COMT in suicidal behavior: analysis in schizophrenia. Brain Res. 1097: 26-30. http://dx.doi.org/10.1016/j.brainres.2006.04.053 PMid:16725119 Durany N, Thome J, Palomo A, Foley P, et al. (1996). Homozygosity at the dopamine D3 receptor gene in schizophrenic patients. Neurosci. Lett. 220: 151-154. http://dx.doi.org/10.1016/S0304-3940(96)13251-1 Ebstein RP, Macciardi F, Heresco-Levi U, Serretti A, et al. (1997). Evidence for an association between the dopamine D3 receptor gene DRD3 and schizophrenia. Hum. Hered. 47: 6-16. http://dx.doi.org/10.1159/000154382 PMid:9017973 Fathalli F, Rouleau GA, Xiong L, Tabbane K, et al. (2008). No association between the DRD3 Ser9Gly polymorphism and schizophrenia. Schizophr. Res. 98: 98-104. http://dx.doi.org/10.1016/j.schres.2007.07.002 PMid:17698325 Hoogendoorn ML, Bakker SC, Schnack HG, Selten JP, et al. (2005). No association between 12 dopaminergic genes and schizophrenia in a large Dutch sample. Am. J. Med. Genet. B. Neuropsychiatr. Genet. 134B: 6-9. http://dx.doi.org/10.1002/ajmg.b.30147 PMid:15635698 Ioannidis JP, Ntzani EE, Trikalinos TA and Contopoulos-Ioannidis DG (2001). Replication validity of genetic association studies. Nat. Genet. 29: 306-309. http://dx.doi.org/10.1038/ng749 PMid:11600885 Jonsson EG, Flyckt L, Burgert E, Crocq MA, et al. (2003). Dopamine D3 receptor gene Ser9Gly variant and schizophrenia: association study and meta-analysis. Psychiatr. Genet. 13: 1-12. http://dx.doi.org/10.1097/00041444-200303000-00001 Jonsson EG, Kaiser R, Brockmoller J, Nimgaonkar VL, et al. (2004). Meta-analysis of the dopamine D3 receptor gene (DRD3) Ser9Gly variant and schizophrenia. Psychiatr. Genet. 14: 9-12. http://dx.doi.org/10.1097/00041444-200403000-00002 Kunugi H, Vallada HP, Hoda F, Kirov G, et al. (1997). No evidence for an association of affective disorders with high- or low-activity allele of catechol-o-methyltransferase gene. Biol. Psychiatry. 42: 282-285. http://dx.doi.org/10.1016/S0006-3223(96)00366-6 Lannfelt L, Sokoloff P, Martres MP, Pilon C, et al. (1992). Amino acid substitution in the dopamine D3 receptor as a useful polymorphism for investigating psychiatric disorders. Psychiatr. Genet. 2: 249-252. http://dx.doi.org/10.1097/00041444-199210000-00003 Le Coniat M, Sokoloff P, Hillion J, Martres MP, et al. (1991). Chromosomal localization of the human D3 dopamine receptor gene. Hum. Genet. 87: 618-620. PMid:1916765 Nagaraj S, Lee KH, Tey NP and Ng CW (2008). Counting and Integration: The Experience of Malaysia, Working Paper Series, No 2008-3. Faculty of Economics and Administration, University of Malaya, Malaya. National Mental Health Registry Report (2003-2005). Department of Psychiatric and Mental Health, Hospital Kuala Lumpur, National Mental Health Registry, Kuala Lumpur. Pal P, Mihanovic M, Molnar S, Xi H, et al. (2009). Association of tagging single nucleotide polymorphisms on 8 candidate genes in dopaminergic pathway with schizophrenia in Croatian population. Croat. Med. J. 50: 361-369. http://dx.doi.org/10.3325/cmj.2009.50.361 PMid:19673036    PMCid:2728391 Scharfetter J, Chaudhry HR, Hornik K, Fuchs K, et al. (1999). Dopamine D3 receptor gene polymorphism and response to clozapine in schizophrenic Pakistani patients. Eur. Neuropsychopharmacol. 10: 17-20. http://dx.doi.org/10.1016/S0924-977X(99)00044-9 Schulze TG and McMahon FJ (2002). Genetic association mapping at the crossroads: which test and why? Overview and practical guidelines. Am. J. Med. Genet. 114: 1-11. http://dx.doi.org/10.1002/ajmg.10042 PMid:11840498 Schwab SG and Wildenauer DB (2008). Research on causes for schizophrenia: are we close? Schizophr. Res. 102: 29-30. http://dx.doi.org/10.1016/j.schres.2008.04.005 Shifman S, Bronstein M, Sternfeld M, Pisante A, et al. (2004). COMT: a common susceptibility gene in bipolar disorder and schizophrenia. Am. J. Med. Genet. B. Neuropsychiatr. Genet. 128B: 61-64. http://dx.doi.org/10.1002/ajmg.b.30032 PMid:15211633 Spurlock G, Williams J, McGuffin P, Aschauer HN, et al. (1998). European multicentre association study of schizophrenia: a study of the DRD2 Ser311Cys and DRD3 Ser9Gly polymorphisms. Am. J. Med. Genet. 81: 24-28. http://dx.doi.org/10.1002/(SICI)1096-8628(19980207)81:1<24::AID-AJMG5>3.0.CO;2-N Staddon S, Arranz MJ, Mancama D, Perez-Nievas F, et al. (2005). Association between dopamine D3 receptor gene polymorphisms and schizophrenia in an isolate population. Schizophr. Res. 73: 49-54. http://dx.doi.org/10.1016/j.schres.2004.06.011 PMid:15567076 Suzuki M, Hurd YL, Sokoloff P, Schwartz JC, et al. (1998). D3 dopamine receptor mRNA is widely expressed in the human brain. Brain Res. 779: 58-74. http://dx.doi.org/10.1016/S0006-8993(97)01078-0 Talkowski ME, Mansour H, Chowdari KV, Wood J, et al. (2006). Novel, replicated associations between dopamine D3 receptor gene polymorphisms and schizophrenia in two independent samples. Biol. Psychiatry 60: 570-577. http://dx.doi.org/10.1016/j.biopsych.2006.04.012 PMid:16893532 Tenhunen J, Salminen M, Lundstrom K, Kiviluoto T, et al. (1994). Genomic organization of the human catechol-o-methyltransferase gene and its expression from two distinct promoters. Eur. J. Biochem. 223: 1049-1059. http://dx.doi.org/10.1111/j.1432-1033.1994.tb19083.x PMid:8055944 Utsunomiya K, Shinkai T, De Luca V, Hwang R, et al. (2008). Genetic association between the dopamine D3 gene polymorphism (Ser9Gly) and schizophrenia in Japanese populations: evidence from a case-control study and meta-analysis. Neurosci. Lett. 444: 161-165. http://dx.doi.org/10.1016/j.neulet.2008.08.005 PMid:18703116 Zhang K, Gao J, An C, Gao X, et al. (2007). An association study between cathechol-o-methyltransferase gene and mental retardation in the Chinese Han population. Neurosci. Lett. 419: 83-87. http://dx.doi.org/10.1016/j.neulet.2007.03.050 PMid:17442488
2010
S. F. Tee, Chow, T. J., Tang, P. Y., and Loh, H. C., Linkage of schizophrenia with TPH2 and 5-HTR2A gene polymorphisms in the Malay population, vol. 9, pp. 1274-1278, 2010.
Abdolmaleky HM, Faraone SV, Glatt SJ and Tsuang MT (2004). Meta-analysis of association between the T102C polymorphism of the 5HT2a receptor gene and schizophrenia. Schizophr. Res. 67: 53-62. http://dx.doi.org/10.1016/S0920-9964(03)00183-X   Andaya BW and Andaya LY (1982). A History of Malaysia. Macmillan, London.   Anonymous (2003-2005). National Mental Health Registry Report. Department of Psychiatric and Mental Health, Hospital Kuala Lumpur: National Mental Health Registry, Kuala Lumpur.   Anttila S, Viikki M, Huuhka K, Huuhka M, et al. (2009). TPH2 polymorphisms may modify clinical picture in treatment-resistant depression. Neurosci. Lett. 464: 43-46. http://dx.doi.org/10.1016/j.neulet.2009.08.018 PMid:19679166   Arango V, Underwood MD and Mann JJ (1997). Postmortem findings in suicide victims. Implications for in vivo imaging studies. Ann. N. Y. Acad. 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Association study of tryptophan hydroxylase 2 gene polymorphisms in panic disorder. Neurosci. Lett. 411: 180-184. http://dx.doi.org/10.1016/j.neulet.2006.09.060 PMid:17123728   Nagaraj S, Lee KH, Tey NP, Ng CW, et al. (2008). Counting and Integration: The Experience of Malaysia, Working Paper Series, No. 2008-3. Faculty of Economics and Administration, University of Malaya, Kuala Lumpur.   Nielsen DA, Virkkunen M, Lappalainen J, Eggert M, et al. (1998). A tryptophan hydroxylase gene marker for suicidality and alcoholism. Arch. Gen. Psychiatry 55: 593-602. http://dx.doi.org/10.1001/archpsyc.55.7.593 PMid:9672049   Pe-as-Lledó EM, Dorado P, Caceres MC, de la Rubia A, et al. (2007). Association between T102C and A-1438G polymorphisms in the serotonin receptor 2A (5-HT2A) gene and schizophrenia: relevance for treatment with antipsychotic drugs. Clin. Chem. Lab. Med. 45: 835-838. PMid:17617023   Prasad KM, Talkowski ME, Chowdari KV, McClain L, et al. (2009). 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