Publications

Bae EY, Lee SY, Kang BK, Lee EJ, et al. (2012). Replication of results of genome-wide association studies on lung cancer susceptibility loci in a Korean population. Respirology 17: 699-706. http://dx.doi.org/10.1111/j.1440-1843.2012.02165.x PMid:22404340   Ginsberg MS (2005). Epidemiology of lung cancer. Semin. Roentgenol. 40: 83-89. http://dx.doi.org/10.1053/j.ro.2005.01.007 PMid:15898406   Girard N, Lou E, Azzoli CG, Reddy R, et al. (2010). Analysis of genetic variants in never-smokers with lung cancer facilitated by an Internet-based blood collection protocol: a preliminary report. Clin. Cancer Res. 16: 755-763. http://dx.doi.org/10.1158/1078-0432.CCR-09-2437 PMid:20068085 PMCid:2808124   Haiman CA, Chen GK, Vachon CM, Canzian F, et al. (2011). A common variant at the TERT-CLPTM1L locus is associated with estrogen receptor-negative breast cancer. Nat. Genet. 43: 1210-1214. http://dx.doi.org/10.1038/ng.985 PMid:22037553 PMCid:3279120   Hardin M, Zielinski J, Wan ES, Hersh CP, et al. (2012). CHRNA3/5, IREB2, and ADCY2 are associated with Severe COPD in Poland. Am. J. Respir. Cell Mol. Biol. [Epub ahead of print]. http://dx.doi.org/10.1165/rcmb.2012-0011OC PMid:22461431   Haugen A, Ryberg D, Mollerup S, Zienolddiny S, et al. (2000). Gene-environment interactions in human lung cancer. Toxicol. Lett. 112-113: 233-237. http://dx.doi.org/10.1016/S0378-4274(99)00275-1   Hung RJ, McKay JD, Gaborieau V, Boffetta P, et al. (2008). A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25. Nature 452: 633-637. http://dx.doi.org/10.1038/nature06885 PMid:18385738   Kiyohara C, Yoshimasu K, Takayama K and Nakanishi Y (2007). Lung cancer susceptibility: are we on our way to identifying a high-risk group? Future Oncol. 3: 617-627. http://dx.doi.org/10.2217/14796694.3.6.617 PMid:18041914   Kollarova H, Janout V and Cizek L (2002). Epidemiology of lung cancer. Biomed. Pap. Med. Fac. Univ. Palacky Olomouc Czech. Repub. 146: 103-114. http://dx.doi.org/10.5507/bp.2002.022 PMid:12572908   Lam WK (2005). Lung cancer in Asian women-the environment and genes. Respirology 10: 408-417. http://dx.doi.org/10.1111/j.1440-1843.2005.00723.x PMid:16135162   Law MH, Montgomery GW, Brown KM, Martin NG, et al. (2012). Meta-analysis combining new and existing data sets confirms that the TERT-CLPTM1L locus influences melanoma risk. J. Invest. Dermatol. 132: 485-487. http://dx.doi.org/10.1038/jid.2011.322 PMid:21993562 PMCid:3258346   Liu Z, Li G, Wei S, Niu J, et al. (2010). Genetic variations in TERT-CLPTM1L genes and risk of squamous cell carcinoma of the head and neck. Carcinogenesis 31: 1977-1981. http://dx.doi.org/10.1093/carcin/bgq179 PMid:20802237 PMCid:2966556   McKay JD, Hung RJ, Gaborieau V, Boffetta P, et al. (2008). Lung cancer susceptibility locus at 5p15.33. Nat. Genet. 40: 1404-1406. http://dx.doi.org/10.1038/ng.254 PMid:18978790 PMCid:2748187   Rafnar T, Sulem P, Stacey SN, Geller F, et al. (2009). Sequence variants at the TERT-CLPTM1L locus associate with many cancer types. Nat. Genet. 41: 221-227. http://dx.doi.org/10.1038/ng.296 PMid:19151717   Sanchez-Cespedes M (2009). Lung cancer biology: a genetic and genomic perspective. Clin. Transl. Oncol. 11: 263-269. http://dx.doi.org/10.1007/s12094-009-0353-7 PMid:19451058   Sugimura H, Tao H, Suzuki M, Mori H, et al. (2011). Genetic susceptibility to lung cancer. Front Biosci. 3: 1463-1477. http://dx.doi.org/10.2741/237   Thill PG, Goswami P, Berchem G and Domon B (2011). Lung cancer statistics in Luxembourg from 1981 to 2008. Bull. Soc. Sci. Med. Grand Duche Luxemb. 43-55. PMid:22272445   Vossen RH, Aten E, Roos A and den Dunnen JT (2009). High-resolution melting analysis (HRMA): more than just sequence variant screening. Hum. Mutat. 30: 860-866. http://dx.doi.org/10.1002/humu.21019 PMid:19418555   Weinrich SL, Pruzan R, Ma L, Ouellette M, et al. (1997). Reconstitution of human telomerase with the template RNA component hTR and the catalytic protein subunit hTRT. Nat. Genet. 17: 498-502. http://dx.doi.org/10.1038/ng1297-498 PMid:9398860   Wu C, Hu Z, Yu D, Huang L, et al. (2009). Genetic variants on chromosome 15q25 associated with lung cancer risk in Chinese populations. Cancer Res. 69: 5065-5072. http://dx.doi.org/10.1158/0008-5472.CAN-09-0081 PMid:19491260

Aberg T, Wozney J and Thesleff I (1997). Expression patterns of bone morphogenetic proteins (Bmps) in the developing mouse tooth suggest roles in morphogenesis and cell differentiation. Dev. Dyn. 210: 383-396. http://dx.doi.org/10.1002/(SICI)1097-0177(199712)210:4<383::AID-AJA3>3.0.CO;2-C   Arte S, Nieminen P, Apajalahti S, Haavikko K, et al. (2001). Characteristics of incisor-premolar hypodontia in families. J. Dent. Res. 80: 1445-1450. http://dx.doi.org/10.1177/00220345010800051201 PMid:11437217   Bei M, Kratochwil K and Maas RL (2000). BMP4 rescues a non-cell-autonomous function of Msx1 in tooth development. Development 127: 4711-4718. PMid:11023873   Capasso M, Ayala F, Russo R, Avvisati RA, et al. (2009). A predicted functional single-nucleotide polymorphism of bone morphogenetic protein-4 gene affects mRNA expression and shows a significant association with cutaneous melanoma in Southern Italian population. J. Cancer Res. Clin. Oncol. 135: 1799-1807. http://dx.doi.org/10.1007/s00432-009-0628-y PMid:19557432   Chen S, Gluhak-Heinrich J, Martinez M, Li T, et al. (2008). Bone morphogenetic protein 2 mediates dentin sialophosphoprotein expression and odontoblast differentiation via NF-Y signaling. J. Biol. Chem. 283: 19359- 19370. http://dx.doi.org/10.1074/jbc.M709492200 PMid:18424784 PMCid:2443643   Choi JY, Shin CS, Hong YC and Kang D (2006). Single-nucleotide polymorphisms and haplotypes of bone morphogenetic protein genes and peripheral bone mineral density in young Korean men and women. Calcif. Tissue Int. 78: 203-211. http://dx.doi.org/10.1007/s00223-005-0139-z PMid:16604289   Feng J, Yang G, Yuan G, Gluhak-Heinrich J, et al. (2011). Abnormalities in the enamel in bmp2-deficient mice. Cells Tissues Organs 194: 216-221. http://dx.doi.org/10.1159/000324644 PMid:21597270 PMCid:3178081   Frazier-Bowers SA, Scott MR, Cavender A, Mensah J, et al. (2002). Mutational analysis of families affected with molar oligodontia. Connect. Tissue Res. 43: 296-300. PMid:12489173   Gabris K, Tarjan I, Csiki P, Konrad F, et al. (2001). Prevalence of congenital hypodontia in the permanent dentition and its treatment. Fogorv. Sz. 94: 137-140. PMid:11573454   Gerits A, Nieminen P, De MS and Carels C (2006). Exclusion of coding region mutations in MSX1, PAX9 and AXIN2 in eight patients with severe oligodontia phenotype. Orthod. Craniofac. Res. 9: 129-136. http://dx.doi.org/10.1111/j.1601-6343.2006.00367.x PMid:16918677   Gluhak-Heinrich J, Guo D, Yang W, Harris MA, et al. (2010). New roles and mechanism of action of BMP4 in postnatal tooth cytodifferentiation. Bone 46: 1533-1545. http://dx.doi.org/10.1016/j.bone.2010.02.024 PMid:20206312 PMCid:2875306   Han D, Gong Y, Wu H, Zhang X, et al. (2008). Novel EDA mutation resulting in X-linked non-syndromic hypodontia and the pattern of EDA-associated isolated tooth agenesis. Eur. J. Med. Genet. 51: 536-546. http://dx.doi.org/10.1016/j.ejmg.2008.06.002 PMid:18657636   Kapadia H, Mues G and D'Souza R (2007). Genes affecting tooth morphogenesis. Orthod. Craniofac. Res. 10: 237-244. http://dx.doi.org/10.1111/j.1601-6343.2007.00407.x PMid:17973693   Kong H, Wang Y, Patel M, Mues G, et al. (2011). Regulation of bmp4 expression in odontogenic mesenchyme: from simple to complex. Cells Tissues Organs 194: 156-160. http://dx.doi.org/10.1159/000324747 PMid:21546760 PMCid:3178073   Lammi L, Halonen K, Pirinen S, Thesleff I, et al. (2003). A missense mutation in PAX9 in a family with distinct phenotype of oligodontia. Eur. J. Hum. Genet. 11: 866-871. http://dx.doi.org/10.1038/sj.ejhg.5201060 PMid:14571272   Lawson KA, Dunn NR, Roelen BA, Zeinstra LM, et al. (1999). Bmp4 is required for the generation of primordial germ cells in the mouse embryo. Genes Dev. 13: 424-436. http://dx.doi.org/10.1101/gad.13.4.424 PMid:10049358 PMCid:316469   Lin JY, Chen YJ, Huang YL, Tang GP, et al. (2008). Association of bone morphogenetic protein 4 gene polymorphisms with nonsyndromic cleft lip with or without cleft palate in Chinese children. DNA Cell Biol. 27: 601-605. http://dx.doi.org/10.1089/dna.2008.0777 PMid:18771417   Liu W, Dong X, Mai M, Seelan RS, et al. (2000). Mutations in AXIN2 cause colorectal cancer with defective mismatch repair by activating beta-catenin/TCF signalling. Nat. Genet. 26: 146-147. http://dx.doi.org/10.1038/79859 PMid:11017067   Meng XL, Wang H, Yang H, Hai Y, et al. (2010). T allele at site 6007 of bone morphogenetic protein-4 gene increases genetic susceptibility to ossification of the posterior longitudinal ligament in male Chinese Han population. Chin. Med. J. 123: 2537-2542.   Nieminen P (2009). Genetic basis of tooth agenesis. J. Exp. Zool. B Mol. Dev. Evol. 312B: 320-342.   Nieminen P, Pekkanen M, Aberg T and Thesleff I (1998). A graphical www-database on gene expression in tooth. Eur. J. Oral Sci. 106: 7-11. PMid:9541196   Noor A, Windpassinger C, Vitcu I, Orlic M, et al. (2009). Oligodontia is caused by mutation in LTBP3, the gene encoding latent TGF-beta binding protein 3. Am. J. Hum. Genet. 84: 519-523. http://dx.doi.org/10.1016/j.ajhg.2009.03.007 PMid:19344874 PMCid:2667979   Ramesh BL, Wilson SG, Dick IM, Islam FM, et al. (2005). Bone mass effects of a BMP4 gene polymorphism in postmenopausal women. Bone 36: 555-561. http://dx.doi.org/10.1016/j.bone.2004.12.005 PMid:15777683   Scarel RM, Trevilatto PC, Di Hipólito O Jr, Camargo LE, et al. (2000). Absence of mutations in the homeodomain of the MSX1 gene in patients with hypodontia. Am. J. Med. Genet. 92: 346-349. http://dx.doi.org/10.1002/1096-8628(20000619)92:5<346::AID-AJMG10>3.0.CO;2-A   Schalk-van der Weide Y, Steen WH and Bosman F (1992). Distribution of missing teeth and tooth morphology in patients with oligodontia. ASDC J. Dent. Child. 59: 133-140. PMid:1583198   Schrauwen I, Thys M, Vanderstraeten K, Fransen E, et al. (2008). Association of bone morphogenetic proteins with otosclerosis. J. Bone Miner. Res. 23: 507-516. http://dx.doi.org/10.1359/jbmr.071112 PMid:18021008 PMCid:2669162   Stockton DW, Das P, Goldenberg M, D'Souza RN, et al. (2000). Mutation of PAX9 is associated with oligodontia. Nat. Genet. 24: 18-19. http://dx.doi.org/10.1038/71634 PMid:10615120   Thesleff I (2003). Epithelial-mesenchymal signalling regulating tooth morphogenesis. J. Cell Sci. 116: 1647-1648. http://dx.doi.org/10.1242/jcs.00410 PMid:12665545   Thomadakis G, Ramoshebi LN, Crooks J, Rueger DC, et al. (1999). Immunolocalization of bone morphogenetic protein-2 and -3 and osteogenic protein-1 during murine tooth root morphogenesis and in other craniofacial structures. Eur. J. Oral Sci. 107: 368-377. http://dx.doi.org/10.1046/j.0909-8836.1999.eos107508.x PMid:10515202   Valdes AM, Hart DJ, Jones KA, Surdulescu G, et al. (2004). Association study of candidate genes for the prevalence and progression of knee osteoarthritis. Arthritis Rheum. 50: 2497-2507. http://dx.doi.org/10.1002/art.20443 PMid:15334463   Valdes AM, Van Oene M, Hart DJ, Surdulescu GL, et al. (2006). Reproducible genetic associations between candidate genes and clinical knee osteoarthritis in men and women. Arthritis Rheum. 54: 533-539. http://dx.doi.org/10.1002/art.21621 PMid:16453284   van den Boogaard MJ, Dorland M, Beemer FA and van Amstel HK (2000). MSX1 mutation is associated with orofacial clefting and tooth agenesis in humans. Nat. Genet. 24: 342-343. http://dx.doi.org/10.1038/74155 PMid:10742093   Wang H, Liu D, Yang Z, Tian B, et al. (2008). Association of bone morphogenetic protein-2 gene polymorphisms with susceptibility to ossification of the posterior longitudinal ligament of the spine and its severity in Chinese patients. Eur. Spine J. 17: 956-964. http://dx.doi.org/10.1007/s00586-008-0651-8 PMid:18389292 PMCid:2443260   Zhang H and Bradley A (1996). Mice deficient for BMP2 are nonviable and have defects in amnion/chorion and cardiac development. Development 122: 2977-2986. PMid:8898212