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“Genetic variants on 17q21 are associated with asthma in a Han Chinese population”, vol. 11, pp. 340-347, 2012.
, Bisgaard H, Bonnelykke K, Sleiman PM, Brasholt M, et al. (2009). Chromosome 17q21 gene variants are associated with asthma and exacerbations but not atopy in early childhood. Am. J. Respir. Crit. Care Med. 179: 179-185.
http://dx.doi.org/10.1164/rccm.200809-1436OC
PMid:19029000
Bouzigon E, Corda E, Aschard H, Dizier MH, et al. (2008). Effect of 17q21 variants and smoking exposure in early-onset asthma. N. Engl. J. Med. 359: 1985-1994.
http://dx.doi.org/10.1056/NEJMoa0806604
PMid:18923164
Eder W, Ege MJ and von Mutius E (2006). The asthma epidemic. N. Engl. J. Med. 355: 2226-2235.
http://dx.doi.org/10.1056/NEJMra054308
PMid:17124020
Flory JH, Sleiman PM, Christie JD, Annaiah K, et al. (2009). 17q12-21 variants interact with smoke exposure as a risk factor for pediatric asthma but are equally associated with early-onset versus late-onset asthma in North Americans of European ancestry. J. Allergy Clin. Immunol. 124: 605-607.
http://dx.doi.org/10.1016/j.jaci.2009.05.047
PMid:19660801
Galanter J, Choudhry S, Eng C, Nazario S, et al. (2008). ORMDL3 gene is associated with asthma in three ethnically diverse populations. Am. J. Respir. Crit. Care Med. 177: 1194-1200.
http://dx.doi.org/10.1164/rccm.200711-1644OC
PMid:18310477 PMCid:2408437
Halapi E, Gudbjartsson DF, Jonsdottir GM, Bjornsdottir US, et al. (2010). A sequence variant on 17q21 is associated with age at onset and severity of asthma. Eur. J. Hum. Genet. 18: 902-908.
http://dx.doi.org/10.1038/ejhg.2010.38
PMid:20372189 PMCid:2987388
Hirota T, Harada M, Sakashita M, Doi S, et al. (2008). Genetic polymorphism regulating ORM1-like 3 (Saccharomyces cerevisiae) expression is associated with childhood atopic asthma in a Japanese population. J. Allergy Clin. Immunol. 121: 769-770.
http://dx.doi.org/10.1016/j.jaci.2007.09.038
PMid:18155279
Hjelmqvist L, Tuson M, Marfany G, Herrero E, et al. (2002). ORMDL proteins are a conserved new family of endoplasmic reticulum membrane proteins. Genome Biol. 3: RESEARCH0027.
Leung TF, Sy HY, Ng MC, Chan IH, et al. (2009). Asthma and atopy are associated with chromosome 17q21 markers in Chinese children. Allergy 64: 621-628.
http://dx.doi.org/10.1111/j.1398-9995.2008.01873.x
PMid:19175592
Li X, Yang XX, Hu NY, Sun JZ, et al. (2011). A risk-associated single nucleotide polymorphism of SMAD7 is common to colorectal, gastric, and lung cancers in a Han Chinese population. Mol. Biol. Rep. 38: 5093-5097.
http://dx.doi.org/10.1007/s11033-010-0656-3
PMid:21221812
Madore AM, Tremblay K, Hudson TJ and Laprise C (2008). Replication of an association between 17q21 SNPs and asthma in a French-Canadian familial collection. Hum. Genet. 123: 93-95.
http://dx.doi.org/10.1007/s00439-007-0444-x
PMid:17992541
Moffatt MF, Kabesch M, Liang L, Dixon AL, et al. (2007). Genetic variants regulating ORMDL3 expression contribute to the risk of childhood asthma. Nature 448: 470-473.
http://dx.doi.org/10.1038/nature06014
PMid:17611496
Ober C and Hoffjan S (2006). Asthma genetics 2006: the long and winding road to gene discovery. Genes Immun. 7: 95-100.
http://dx.doi.org/10.1038/sj.gene.6364284
PMid:16395390
Sleiman PM, Annaiah K, Imielinski M, Bradfield JP, et al. (2008). ORMDL3 variants associated with asthma susceptibility in North Americans of European ancestry. J. Allergy Clin. Immunol. 122: 1225-1227.
http://dx.doi.org/10.1016/j.jaci.2008.06.041
PMid:18760456
Tavendale R, MacGregor DF, Mukhopadhyay S and Palmer CN (2008). A polymorphism controlling ORMDL3 expression is associated with asthma that is poorly controlled by current medications. J. Allergy Clin. Immunol. 121: 860-863.
http://dx.doi.org/10.1016/j.jaci.2008.01.015
PMid:18395550
Wjst M (2008). ORMDL3 - guilt by association? Clin. Exp. Allergy 38: 1579-1581.
http://dx.doi.org/10.1111/j.1365-2222.2008.03086.x
Wu H, Romieu I, Sienra-Monge JJ, Li H, et al. (2009). Genetic variation in ORM1-like 3 (ORMDL3) and gasdermin-like (GSDML) and childhood asthma. Allergy 64: 629-635.
http://dx.doi.org/10.1111/j.1398-9995.2008.01912.x
PMid:19133921 PMCid:2697826