Publications
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“Short aggrecan gene repetitive alleles associated with lumbar degenerative disc disease in Turkish patients”, vol. 10, pp. 1923-1930, 2011.
, Battie MC, Videman T, Kaprio J, Gibbons LE, et al. (2009). The twin spine study: contributions to a changing view of disc degeneration. Spine J. 9: 47-59.
http://dx.doi.org/10.1016/j.spinee.2008.11.011
PMid:19111259
Boden SD, Davis DO, Dina TS, Patronas NJ, et al. (1990). Abnormal magnetic-resonance scans of the lumbar spine in asymptomatic subjects. A prospective investigation. J. Bone Joint Surg. Am. 72: 403-408.
PMid:2312537
Doege KJ, Coulter SN, Meek LM, Maslen K, et al. (1997). A human-specific polymorphism in the coding region of the aggrecan gene. Variable number of tandem repeats produce a range of core protein sizes in the general population. J. Biol. Chem. 272: 13974-13979.
http://dx.doi.org/10.1074/jbc.272.21.13974
PMid:9153261
Horton WE Jr, Lethbridge-Cejku M, Hochberg MC, Balakir R, et al. (1998). An association between an aggrecan polymorphic allele and bilateral hand osteoarthritis in elderly white men: data from the Baltimore Longitudinal Study of Aging (BLSA). Osteoarthritis Cartilage 6: 245-251.
http://dx.doi.org/10.1053/joca.1998.0117
Kalichman L and Hunter DJ (2008). The genetics of intervertebral disc degeneration. Associated genes. Joint Bone Spine 75: 388-396.
http://dx.doi.org/10.1016/j.jbspin.2007.11.002
PMid:18485784
Kämäräinen OP, Solovieva S, Vehmas T, Luoma K, et al. (2006). Aggrecan core protein of a certain length is protective against hand osteoarthritis. Osteoarthritis Cartilage 14: 1075-1080.
http://dx.doi.org/10.1016/j.joca.2006.04.005
PMid:16713721
Kawaguchi Y, Osada R, Kanamori M, Ishihara H, et al. (1999). Association between an aggrecan gene polymorphism and lumbar disc degeneration. Spine 24: 2456-2460.
http://dx.doi.org/10.1097/00007632-199912010-00006
PMid:10626307
Kelsey JL, Githens PB, O’Conner T, Weil U, et al. (1984). Acute prolapsed lumbar intervertebral disc. An epidemiologic study with special reference to driving automobiles and cigarette smoking. Spine 9: 608-613.
http://dx.doi.org/10.1097/00007632-198409000-00012
PMid:6495031
Kirk KM, Doege KJ, Hecht J, Bellamy N, et al. (2003). Osteoarthritis of the hands, hips and knees in an Australian twin sample - evidence of association with the aggrecan VNTR polymorphism. Twin Res. 6: 62-66.
http://dx.doi.org/10.1375/136905203762687915
PMid:12626230
Kujala UM, Taimela S, Viljanen T, Jutila H, et al. (1996). Physical loading and performance as predictors of back pain in healthy adults. A 5-year prospective study. Eur. J. Appl. Physiol. Occup. Physiol. 73: 452-458.
http://dx.doi.org/10.1007/BF00334423
PMid:8803506
Luoma K, Riihimaki H, Luukkonen R, Raininko R, et al. (2000). Low back pain in relation to lumbar disc degeneration. Spine 25: 487-492.
http://dx.doi.org/10.1097/00007632-200002150-00016
PMid:10707396
Maniadakis N and Gray A (2000). The economic burden of back pain in the UK. Pain 84: 95-103.
http://dx.doi.org/10.1016/S0304-3959(99)00187-6
Matsui H, Tsuji H and Terahata N (1990). Juvenile lumbar herniated nucleus pulposus in monozygotic twins. Spine 15: 1228-1230.
http://dx.doi.org/10.1097/00007632-199011010-00025
PMid:2267621
Matsui H, Terahata N, Tsuji H, Hirano N, et al. (1992). Familial predisposition and clustering for juvenile lumbar disc herniation. Spine 17: 1323-1328.
http://dx.doi.org/10.1097/00007632-199211000-00011
PMid:1462208
Matsui H, Kanamori M, Ishihara H, Yudoh K, et al. (1998). Familial predisposition for lumbar degenerative disc disease. A case-control study. Spine 23: 1029-1034.
http://dx.doi.org/10.1097/00007632-199805010-00013
PMid:9589542
Noponen-Hietala N, Kyllonen E, Mannikko M, Ilkko E, et al. (2003). Sequence variations in the collagen IX and XI genes are associated with degenerative lumbar spinal stenosis. Ann. Rheum Dis. 62: 1208-1214.
http://dx.doi.org/10.1136/ard.2003.008334
PMid:14644861 PMCid:1754404
Pope MH and Hansson TH (1992). Vibration of the spine and low back pain. Clin. Orthop. Relat. Res. 27: 49-59.
Richardson JK, Chung T, Schultz JS and Hurvitz E (1997). A familial predisposition toward lumbar disc injury. Spine 22: 1487-1492.
http://dx.doi.org/10.1097/00007632-199707010-00012
PMid:9231968
Roughley PJ, Alini M and Antoniou J (2002). The role of proteoglycans in aging, degeneration and repair of the intervertebral disc. Biochem. Soc. Trans. 30: 869-874.
http://dx.doi.org/10.1042/BST0300869
Roughley P, Martens D, Rantakokko J, Alini M, et al. (2006). The involvement of aggrecan polymorphism in degeneration of human intervertebral disc and articular cartilage. Eur. Cell Mater. 11: 1-7.
PMid:16425147
Schneiderman G, Flannigan B, Kingston S, Thomas J, et al. (1987). Magnetic resonance imaging in the diagnosis of disc degeneration: correlation with discography. Spine 12: 276-281.
http://dx.doi.org/10.1097/00007632-198704000-00016
PMid:2954224
Simmons ED Jr, Guntupalli M, Kowalski JM, Braun F, et al. (1996). Familial predisposition for degenerative disc disease. A case-control study. Spine 21: 1527-1529.
http://dx.doi.org/10.1097/00007632-199607010-00007
PMid:8817779
Solovieva S, Noponen N, Mannikko M, Leino-Arjas P, et al. (2007). Association between the aggrecan gene variable number of tandem repeats polymorphism and intervertebral disc degeneration. Spine 32: 1700-1705.
http://dx.doi.org/10.1097/BRS.0b013e3180b9ed51
PMid:17632389
Videman T, Saarela J, Kaprio J, Nakki A, et al. (2009). Associations of 25 structural, degradative, and inflammatory candidate genes with lumbar disc desiccation, bulging, and height narrowing. Arthritis Rheum. 60: 470-481.
http://dx.doi.org/10.1002/art.24268
Watanabe H, Yamada Y and Kimata K (1998). Roles of aggrecan, a large chondroitin sulfate proteoglycan, in cartilage structure and function. J. Biochem. 124: 687-693.
PMid:9756610
Wiesel SW, Weinstein JN, Herkowitz H et al. (1996). The Lumbar Spine. 2nd edn. WB Saunders Press, Philadelphia.
Zamani MH and MacEwen GD (1982). Herniation of the lumbar disc in children and adolescents. J. Pediatr. Orthop. 2: 528-533.
http://dx.doi.org/10.1097/01241398-198212000-00012
PMid:6219127