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2011
C. A. F. Aiub, Gadermaier, G., Silva, I. O., Felzenszwalb, I., Pinto, L. F. R., Ferreira, F., and Eckl, P., N-nitrosodiethylamine genotoxicity evaluation: a cytochrome P450 induction study in rat hepatocytes, vol. 10, pp. 2340-2348, 2011.
Aiub CA, Pinto LF and Felzenszwalb I (2003). N-Nitrosodiethylamine mutagenicity at low concentrations. Toxicol. Lett. 145: 36-45. http://dx.doi.org/10.1016/S0378-4274(03)00263-7 Aiub CA, Mazzei JL, Pinto LF and Felzenszwalb I (2004a). Participation of BER and NER pathways in the repair of DNA lesions induced at low N-nitrosodiethylamine concentrations. Toxicol. Lett. 154: 133-142. http://dx.doi.org/10.1016/j.toxlet.2004.07.012 PMid:15475187 Aiub CA, Pinto LF and Felzenszwalb I (2004b). Standardization of conditions for the metabolic activation of N-nitrosodiethylamine in mutagenicity tests. Genet. Mol. Res. 3: 264-272. PMid:15266397 Aiub CA, Mazzei JL, Pinto LF and Felzenszwalb I (2006). Evaluation of nitroreductase and acetyltransferase participation in N-nitrosodiethylamine genotoxicity. Chem. Biol. Interact. 161: 146-154. http://dx.doi.org/10.1016/j.cbi.2006.03.012 PMid:16720019 Aiub CA, Pinto LF and Felzenszwalb I (2009). DNA-repair genes and vitamin E in the prevention of N-nitrosodiethylamine mutagenicity. Cell Biol. Toxicol. 25: 393-402. http://dx.doi.org/10.1007/s10565-008-9093-7 PMid:18581242 Camus AM, Geneste O, Honkakoski P, Bereziat JC, et al. (1993). High variability of nitrosamine metabolism among individuals: role of cytochromes P450 2A6 and 2E1 in the dealkylation of N-nitrosodimethylamine and N-nitrosodiethylamine in mice and humans. Mol. Carcinog. 7: 268-275. http://dx.doi.org/10.1002/mc.2940070410 PMid:8352885 Eckl PM and Riegler D (1997). Levels of chromosomal damage in hepatocytes of wild rats living within the area of a waste disposal plant. Sci. Total Environ. 196: 141-149. http://dx.doi.org/10.1016/S0048-9697(96)05413-7 Khader M, Eckl PM and Bresgen N (2007). Effects of aqueous extracts of medicinal plants on MNNG-treated rat hepatocytes in primary cultures. J. Ethnopharmacol. 112: 199-202. http://dx.doi.org/10.1016/j.jep.2007.01.027 PMid:17324542 Khader M, Bresgen N and Eckl PM (2009). In vitro toxicological properties of thymoquinone. Food Chem. Toxicol. 47: 129-133. http://dx.doi.org/10.1016/j.fct.2008.10.019 PMid:19010375 Koskela S, Hakkola J, Hukkanen J, Pelkonen O, et al. (1999). Expression of CYP2A genes in human liver and extrahepatic tissues. Biochem. Pharmacol. 57: 1407-1413. http://dx.doi.org/10.1016/S0006-2952(99)00015-5 Lazarová M, Lábaj J, Eckl P, Kogan G, et al. (2006). Effects of dietary intake of a fungal beta-D-glucan derivative on the level of DNA damage induced in primary rat hepatocytes by various carcinogens. Nutr. Cancer 56: 113-122. http://dx.doi.org/10.1207/s15327914nc5601_15 PMid:17176225 Lim IK (2003). Spectrum of molecular changes during hepatocarcinogenesis induced by DEN and other chemicals in Fisher 344 male rats [Mechanisms of Ageing and Development 123 (2002) 1665-1680]. Mech. Ageing Dev. 124: 697-708. http://dx.doi.org/10.1016/S0047-6374(03)00010-1 Liu LL, Gong LK, Qi XM, Cai Y, et al. (2005). Altered expression of cytochrome P450 and possible correlation with preneoplastic changes in early stage of rat hepatocarcinogenesis. Acta Pharmacol. Sin. 26: 737-744. http://dx.doi.org/10.1111/j.1745-7254.2005.00737.x PMid:15916741 Ribeiro Pinto LF (2000). Differences between isoamyl alcohol and ethanol on the metabolism and DNA ethylation of N-nitrosodiethylamine in the rat. Toxicology 151: 73-79. http://dx.doi.org/10.1016/S0300-483X(00)00297-3 Ribeiro Pinto LF and Swann PF (1997). Opium and oesophageal cancer: effect of morphine and opium on the metabolism of N-nitrosodimethylamine and N-nitrosodiethylamine in the rat. Carcinogenesis 18: 365-369. http://dx.doi.org/10.1093/carcin/18.2.365 PMid:9054630 Shu L and Hollenberg PF (1997). Alkylation of cellular macromolecules and target specificity of carcinogenic nitrosodialkylamines: metabolic activation by cytochromes P450 2B1 and 2E1. Carcinogenesis 18: 801-810. http://dx.doi.org/10.1093/carcin/18.4.801 PMid:9111218