Zhi-Long-Huo-Xue-Tong-Yu

Zhi-Long-Huo-Xue-Tong-Yu modulates mitochondrial fission through the ROCK1 pathway in mitochondrial dysfunction caused by streptozotocin-induced diabetic kidney injury

W. H. Wu, Zhang, M. P., Yang, S. J., Liu, Q., Bai, X., Qin, J. H., Peng, B., Ou, S. T., Liu, J., Zhao, C. Y., Zhang, Q., Hu, Q. D., and Xue, L., Zhi-Long-Huo-Xue-Tong-Yu modulates mitochondrial fission through the ROCK1 pathway in mitochondrial dysfunction caused by streptozotocin-induced diabetic kidney injury, vol. 14, pp. 4593-4606, 2015.

Zhi-Long-Huo-Xue-Tong-Yu (ZLHXTY) is a defined mixture of 5 herbs developed by Professor S.J. Yang according to the Buyang Huanwu decoction method, which has been recorded in the Yilingaicuo. This study investigated the renoprotective effects of ZLHXTY on mitochondrial dysfunction induced by diabetic kidney injury in a diabetic rat model. Diabetes was induced by a single intravenous injection of streptozotocin. Rats were daily fed either ZLHXTY or vehicle beginning in the 1st week after injection.

Subscribe to Zhi-Long-Huo-Xue-Tong-Yu