DNA repair gene polymorphisms and susceptibility to familial breast cancer in a group of patients from Campinas, Brazil
“DNA repair gene polymorphisms and susceptibility to familial breast cancer in a group of patients from Campinas, Brazil”, vol. 4, pp. 771-782, 2005.
, Several studies have reported that the genes involved in DNA repair and in the maintenance of genome integrity play a crucial role in protecting against mutations that lead to cancer. Epidemiologic evidence has shown that the inheritance of genetic variants at one or more loci results in a reduced DNA repair capacity and in an increased risk of cancer.