X-ray repair cross-complementing group 1 rs25487

XRCC1 rs25487 polymorphism is associated with lung cancer risk in epidemiologically susceptible Chinese people

X. Wang, Ma, K. W., Zhao, Y. G., Wang, G. J., and Li, W., XRCC1 rs25487 polymorphism is associated with lung cancer risk in epidemiologically susceptible Chinese people, vol. 14, pp. 15530-15538, 2015.

Base excision repair (BER) plays an important role in maintaining genome integrity and anti-cancer drug resistance. Single nu­cleotide polymorphisms (SNPs) in BER genes were detected in 500 lung cancer patients and 500 cancer-free controls. A logistic regression model was applied to analyze the relationship between lung cancer susceptibility and BER SNPs coupled with a wide range of epidemiological factors in a Chinese population.

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