VRK2 gene

Association of the VRK2 gene rs3732136 polymorphism with schizophrenia in a Northwest Chinese Han population

B. Zhang, Gao, C. Y., Zhang, H. B., Yang, B., Yin, J. F., Wei, S. G., Zhu, Y. S., Jia, X. N., and Li, S. B., Association of the VRK2 gene rs3732136 polymorphism with schizophrenia in a Northwest Chinese Han population, vol. 14, pp. 9404-9411, 2015.

Previous studies have found that the vaccinia related kinase 2 gene (VRK2) polymorphism was associated with schizophrenia (SCZ) in the worldwide population. This association was further supported by VRK2 mRNA expression patterns and brain structure variations. Here, we analyzed four single nucleotide polymorphisms (SNPs) of the VRK2 gene in a total population of 893 samples, consisting of 360 patients with SCZ and 533 healthy controls of Han Chinese descent using the SNPscan method. Single SNP, haplotype, and gender-specific association analyses were performed.

Subscribe to VRK2 gene