VEGF

Effect of ozone on vascular endothelial growth factor (VEGF) and related inflammatory cytokines in rats with diabetic retinopathy

T. Y. Xie, Yan, W., Lou, J., Chen, X. Y., Xie, T. Y., Yan, W., Lou, J., and Chen, X. Y., Effect of ozone on vascular endothelial growth factor (VEGF) and related inflammatory cytokines in rats with diabetic retinopathy, vol. 15, p. -, 2016.

The aim of this study was to investigate the effect of ozone on inflammatory cytokines in diabetic retinopathy (DR) rats. Male rats (40) weighing 300-360 g were included in this study. Thirty rats were randomly divided into the model and ozone groups after DR was induced by streptozotocin. Ten rats served as the blank group. After the diabetic models were established for one month, the rats in the ozone group were treated with 50 mg/kg ozone coloclysis for one month (three times a week).

Association between the expression of HIF-1α and VEGF and prognostic implications in primary liver cancer

L. Y. Guo, Zhu, P., Jin, X. P., Guo, L. Y., Zhu, P., and Jin, X. P., Association between the expression of HIF-1α and VEGF and prognostic implications in primary liver cancer, vol. 15, p. -, 2016.

The goal of this study was to investigate the expression of hypoxia-inducible factor-1α (HIF-1α) and vascular endothelial growth factor (VEGF) in primary liver cancer (PLC) and their association with prognosis. Tumor tissue, non-tumor tissue, and blood samples of 75 PLC patients were collected. Blood samples of 20 volunteers were also collected as healthy controls. Real-time quantitative reverse transcription-polymerase chain reaction was used to analyze the mRNA levels of HIF-1α and VEGF in the tissues. Protein expression of HIF-1α and VEGF was analyzed by immunohistochemistry.

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