VEGF

Correlation between matrix metalloproteinase-9 and vascular endothelial growth factor expression in lung adenocarcinoma

Y. L. Wen and Li, L., Correlation between matrix metalloproteinase-9 and vascular endothelial growth factor expression in lung adenocarcinoma, vol. 14, pp. 19342-19348, 2015.

The aim of this study was to investigate the correlation between the expression of matrix metalloproteinase-9 (MMP-9) and vascular endothelial growth factor (VEGF) and clinicopathological features of lung adenocarcinoma. The expression of MMP-9 and VEGF was evaluated by immunohistochemistry of 30 samples from lung adenocarcinoma patients and 12 paratumoral (normal) tissue samples. In addition, the change in VEGF or MMP-9 expression after MMP-9 or VEGF blockade, respectively, was measured using western blot in lung adenocarcinoma A549 cells.

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