Vascular endothelial growth factor

Shock wave treatment enhances endothelial proliferation via autocrine vascular endothelial growth factor

Y. Z. Peng, Zheng, K., Yang, P., Wang, Y., Li, R. J., Li, L., Pan, J. H., and Guo, T., Shock wave treatment enhances endothelial proliferation via autocrine vascular endothelial growth factor, vol. 14, pp. 19203-19210, 2015.

Extracorporeal cardiac shock wave (SW) therapy is an effective, safe, and non-invasive therapeutic strategy for severe coronary artery disease. Shock wave therapy might affect cardiac tissues because of its ability to promote angiogenesis. In this report, we investigated if the up-regulation of vascular endothelial growth factor (VEGF) by SW therapy is involved in cell proliferation in cultured endothelial cells. After human umbilical vein endothelial cells were treated with SW, the expression and secretion of VEGF as well as cell proliferation were analyzed.

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