Vascular endothelial growth factor

Predictive value of vascular endothelial growth factor polymorphisms on the risk of renal cell carcinomas

W. Xian, Zheng, H., and Wu, W. J., Predictive value of vascular endothelial growth factor polymorphisms on the risk of renal cell carcinomas, vol. 14, pp. 7634-7642, 2015.

We conducted a case-control study in a Chinese population to assess whether 5 common single-nucleotide polymor­phisms in the vascular endothelial growth factor gene (VEGF) affect the risk of renal cell carcinoma (RCC). The study population in­cluded 266 RCC patients who were newly diagnosed and histologi­cally confirmed to have RCC as well as 532 cancer-free controls. Genotyping of VEGF -2578C/A, -1156G/A, +1612G/A, +936C/T, and -634G/C was conducted by polymerase chain reaction-restric­tion fragment length polymorphism.

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