Vascular endothelial growth factor

Vascular endothelial growth factor +936C/T polymorphism and cancer risk in Asians: a meta-analysis

X. L. Liu, Yang, Q. F., and Kong, B. H., Vascular endothelial growth factor +936C/T polymorphism and cancer risk in Asians: a meta-analysis, vol. 12, pp. 1924-1933, 2013.

Vascular endothelial growth factor (VEGF), the most important regulator of angiogenesis and vascular permeability, is involved in various steps of carcinogenesis. The +936C/T polymorphism of the VEGF gene has been reported to affect the VEGF protein level and to be related to the susceptibility of cancer. However, the results of published studies, as well as the subsequent meta-analyses, remain contradictory. We investigated the association between VEGF +936C/T polymorphism and cancer risk in the Asian population.

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