UL2

Molecular characterization of the pseudorabies virus UL2 gene

M. S. Cai, Wang, B. Y., Cui, W., Zhao, Z. Y., Chen, J. H., Wen, X. M., Li, Z., and Li, M. L., “Molecular characterization of the pseudorabies virus UL2 gene”, vol. 12, pp. 4147-4161, 2013.

A 948-bp sequence of the UL2 gene was amplified from the pseudorabies virus (PRV) Becker strain genome using polymerase chain reaction, and the gene identity was confirmed through further cloning and sequencing. Bioinformatic analysis indicated that the PRV UL2 gene encodes a putative polypeptide with 315-amino acid residues. Its encoding protein, designated UL2, has a conserved uracil-DNA glycosylase (UDG)_F1 domain, which is closely related to the herpesvirus UDG family and is highly conserved among its counterparts encoded by UDG genes.

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