Treatment outcome

Genetic variability of ERCC1 and ERCC2 genes involved in the nucleotide excision repair pathway influences the treatment outcome of gastric cancer

D. L. Zheng, Tang, G. D., Chen, Y. N., Zhang, T., Qin, M. B., Zheng, D. L., Tang, G. D., Chen, Y. N., Zhang, T., Qin, M. B., Zheng, D. L., Tang, G. D., Chen, Y. N., Zhang, T., and Qin, M. B., Genetic variability of ERCC1 and ERCC2 genes involved in the nucleotide excision repair pathway influences the treatment outcome of gastric cancer, vol. 15, p. -, 2016.

We conducted a prospective study to investigate whether ERCC1 rs11615 and rs3212986 and ERCC2 rs13181 and rs1799793 gene polymorphisms could serve as potential biomarkers for the prognosis of gastric cancer. Between January 2010 and December 2012, 246 patients with pathologically proven gastric cancer who were receiving platinum-based chemotherapy were recruited from the First Affiliated Hospital of Guangxi Medical University.

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