Transcriptional regulation

H3K27me3 may be associated with Oct4 and Sox2 in mouse preimplantation embryos

F. - R. Wu, Zhang, Y., Ding, B., Lei, X. - H., Huang, J. - C., Wang, C. - H., Liu, Y., Wang, R., and Li, W. - Y., H3K27me3 may be associated with Oct4 and Sox2 in mouse preimplantation embryos, vol. 13, pp. 10121-10129, 2014.

As a core member of polycomb repressive complex 2, the transcription and enzyme activity of enhancer of zeste homolog 2 (Ezh2) is directly involved in the trimethylation of lysine 27 on histone H3. In this study, the fluorescence intensity of H3K27me3 in mouse in vivo morulae and blastocysts was compared by indirect immunofluorescence staining. We found that demethylation of H3K27me3 occurred during the blastocyst stage. Real-time polymerase chain reaction was performed to investigate Ezh2 expression in oocytes and in preimplantation embryos.

Genome-wide partial correlation analysis of Escherichia coli microarray data

D. F. T. Veiga, Vicente, F. F. R., Grivet, M., de la Fuente, A., and Vasconcelos, A. T. R., Genome-wide partial correlation analysis of Escherichia coli microarray data, vol. 6, pp. 730-742, 2007.

Transcriptional control is an essential regulatory mechanism employed by bacteria. Much about transcriptional regulation remains to be discovered, even for the most widely studied bacterium, Escherichia coli. In the present study, we made a genome-wide low-order partial correlation analysis of E. coli microarray data with the purpose of recovering regulatory interactions from transcriptome data.

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