Transcriptional regulation

Transcriptional regulation of catabolic pathways for aromatic compounds in Corynebacterium glutamicum

K. Brinkrolf, Brune, I., and Tauch, A., Transcriptional regulation of catabolic pathways for aromatic compounds in Corynebacterium glutamicum, vol. 5. pp. 773-789, 2006.

Corynebacterium glutamicum is a gram-positive soil microorganism able to utilize a large variety of aromatic compounds as the sole carbon source. The corresponding catabolic routes are associated with multiple ring-fission dioxygenases and among other channeling reactions, include the gentisate pathway, the protocatechuate and catechol branches of the β-ketoadipate pathway and two potential hydroxyquinol pathways. Genes encoding the enzymatic machinery for the bioconversion of aromatic compounds are organized in several clusters in the C. glutamicum genome.

Genome-wide partial correlation analysis of Escherichia coli microarray data

D. F. T. Veiga, Vicente, F. F. R., Grivet, M., de la Fuente, A., and Vasconcelos, A. T. R., Genome-wide partial correlation analysis of Escherichia coli microarray data, vol. 6, pp. 730-742, 2007.

Transcriptional control is an essential regulatory mechanism employed by bacteria. Much about transcriptional regulation remains to be discovered, even for the most widely studied bacterium, Escherichia coli. In the present study, we made a genome-wide low-order partial correlation analysis of E. coli microarray data with the purpose of recovering regulatory interactions from transcriptome data.

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