Transcription factors

Transcriptome network-based method to identify genes associated with unruptured intracranial aneurysms

L. Wei, Gao, Y. J., Wei, S. P., Zhang, Y. F., Zhang, W. F., Jiang, J. X., Sun, Z. Y., and Xu, W., Transcriptome network-based method to identify genes associated with unruptured intracranial aneurysms, vol. 12, pp. 3263-3273, 2013.

Intracranial aneurysm is a balloon or sac-like dilatation of blood vessels inside the brain. Despite their importance, the biological mechanisms of intracranial aneurysms are not totally understood. We used public genome-wide gene expression profile data to identify potential genes that are involved in intracranial aneurysm in order to construct a regulation network. Some of the transcription factors and target genes that we identified in this network had been identified as related to intracranial aneurysm in previous studies.

Oxidative stress response in Paracoccidioides brasiliensis

É. G. Campos, Dantas, Ada Silva, Brigido, Mde Macedo, Brigido, Mde Macedo, Felipe, M. Sueli S., and Jesuino, R. Santos Amo, Oxidative stress response in Paracoccidioides brasiliensis, vol. 4, pp. 409-429, 2005.

Survival of pathogenic fungi inside human hosts depends on evasion from the host immune system and adaptation to the host environment. Among different insults that Paracoccidioides brasiliensis has to handle are reactive oxygen and nitrogen species produced by the human host cells, and by its own metabolism. Knowing how the parasite deals with reactive species is important to understand how it establishes infection and survives within humans. The initiative to describe the P.

Subscribe to Transcription factors