Transcription factor

Gli1 expression in pancreatic ductal adenocarcinoma and its clinical significance

Y. Abula, Yi, C., Wang, X. - Y., Wang, M., Qin, R. - Y., Guo, Y. - Q., Lin, H., and Li, H. - J., Gli1 expression in pancreatic ductal adenocarcinoma and its clinical significance, vol. 14, pp. 12323-12329, 2015.

The aim of this study was to explore the correlation between the expression levels of Gli1 and p53 in pancreatic ductal adenocarcinoma (PDAC) and its pathological significance. Immunohistochemistry (IHC) was employed to measure the expression level of Gli1 and p53 in 85 sets of paraffin-embedded PDAC and corresponding para-carcinoma tissue specimens. The relationship between these results and the respective patients’ clinicopathologic parameters was analyzed.

Cloning and transformation of INDUCER of CBF EXPRESSION1 (ICE1) in tomato

X. H. Yu, Juan, J. X., Gao, Z. L., Zhang, Y., Li, W. Y., and Jiang, X. M., Cloning and transformation of INDUCER of CBF EXPRESSION1 (ICE1) in tomato, vol. 14, pp. 13131-13143, 2015.

The tomato plant (Solanum lycopersicum Mill.) is sensitive to cold, and low field temperatures can result in shortened growth periods and decreased crop yield. Transcription of CRT/DRE-binding factor (CBF) is regulated by INDUCER of CBF EXPRESSION1 (ICE1). CBF activates many downstream genes that confer cold tolerance on plants. ICE1 has been used in genetic engineering to improve cold-resistance in several plant species.

Genomic identification of group A bZIP transcription factors and their responses to abiotic stress in carrot

F. Que, Wang, G. L., Huang, Y., Xu, Z. S., Wang, F., and Xiong, A. S., Genomic identification of group A bZIP transcription factors and their responses to abiotic stress in carrot, vol. 14, pp. 13274-13288, 2015.

The basic-region/leucine-zipper (bZIP) family is one of the major transcription factor (TF) families associated with responses to abiotic stresses. Many members of group A in this family have been extensively examined and are reported to perform significant functions in ABA signaling as well as in responses to abiotic stresses. In this study, 10 bZIP factors in carrot were classified into group A based on their DNA-binding domains. The cis-acting regulatory elements and folding states of these 10 factors were analyzed.

OsMYB511 encodes a MYB domain transcription activator early regulated by abiotic stress in rice

P. Huang, Chen, H., Mu, R., Yuan, X., Zhang, H. S., and Huang, J., OsMYB511 encodes a MYB domain transcription activator early regulated by abiotic stress in rice, vol. 14, pp. 9506-9517, 2015.

The MYB-domain proteins exist universally across diverse organisms and regulate numerous processes during the plant life cycle. In the present research, a full-length MYB gene OsMYB511 was identified from rice seedlings through microarray data. Induction of OsMYB511 by cold stress was dramatic in japonica cultivar Jiucaiqing as compared to indica IR26.

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