Total peony glycoside

Effect of total peony glucoside pretreatment on NF-κB and ICAM-1 expression in myocardial tissue of rat with myocardial ischemia-reperfusion injury

L. Lu, Wei, P., Cao, Y., Zhang, Q., Liu, M., Liu, X. D., Wang, Z. L., Zhang, P. Y., Lu, L., Wei, P., Cao, Y., Zhang, Q., Liu, M., Liu, X. D., Wang, Z. L., and Zhang, P. Y., “Effect of total peony glucoside pretreatment on NF-κB and ICAM-1 expression in myocardial tissue of rat with myocardial ischemia-reperfusion injury”, vol. 15, no. 4, p. -, 2016.

INTRODUCTION

Fast, effective recovery of the coronary blood flow, after myocardial ischemia, is an effective method to treat this ischemia. However, myocardial ischemia-reperfusion (I/R) can aggravate ischemia-induced cardiac dysfunction and myocardial cell damage, leading to intracellular calcium overload, apoptosis, and inflammation. Therefore, clarifying its mechanism is important for the prevention of myocardial I/R injury.

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