Toll-like receptor 4 signaling pathway

Attenuated mRNA expression of lipid metabolism genes in primary hepatocytes following lipopolysaccharide treatment in dairy cows

Y. Y. Wang, Li, H. P., Wang, X. J., Jiang, Q. D., Geng, J., Wang, L. F., Guo, Y. J., Lu, W. F., Zhu, H. S., and Yang, G. Y., Attenuated mRNA expression of lipid metabolism genes in primary hepatocytes following lipopolysaccharide treatment in dairy cows, vol. 14, pp. 3718-3728, 2015.

The influence of ruminal acidosis on ruminal microbiology and metabolite production has received considerable attention, but little is known regarding the systemic manifestations that arise from ruminal acidosis. Lipopolysaccharide (LPS) is released in the gastrointestinal tract upon ingestion of high-grain or high-fat diets, and it has been implicated in the etiology of multiple energy- and lipid-related metabolic disturbances in ruminants. The liver plays a crucial role in the acute phase response to intruding pathogens.

Subscribe to Toll-like receptor 4 signaling pathway