TNF-α -308 A/G and -238 A/G polymorphisms and susceptibility to glaucoma: a meta-analysis
The purpose of this study was to examine whether tumor necrosis factor-α (TNF-α) -308 A/G and -238 A/G polymorphisms confer susceptibility to glaucoma. A meta-analysis was conducted examining the association between TNF-α -308 A/G and -238 A/G polymorphisms and glaucoma. A total of 13 studies on TNF-α -308 A/G and 238 A/G polymorphisms were included in this meta-analysis. The meta-analysis revealed no association between the TNF-α -308 A allele and glaucoma [odds ratio (OR) = 1.403, 95% confidence interval (CI) = 0.784-2.513, P = 0.254].