TIGIT

Construction and characterization of recombinant adenovirus carrying a mouse TIGIT-GFP gene

J. M. Zheng, Cui, J. L., He, W. T., Yu, D. W., Gao, Y., Wang, L., Chen, Z. K., and Zhou, H. M., Construction and characterization of recombinant adenovirus carrying a mouse TIGIT-GFP gene, vol. 14, pp. 18650-18661, 2015.

Recombinant adenovirus vector systems have been used extensively in protein research and gene therapy. However, the construction and characterization of recombinant adenovirus is a tedious and time-consuming process. TIGIT is a recently discovered immunosuppressive molecule that plays an important role in maintaining immunological balance. The construction of recombinant adenovirus mediating TIGIT expression must be simplified to facilitate its use in the study of TIGIT.

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