TGFB1

Role of TGFB1 polymorphism in the development of metastatic brain tumors in non-small cell lung cancer patients

H. B. Wang, Song, W. G., Liu, H. Q., Fang, F., and Xiao, Y., Role of TGFB1 polymorphism in the development of metastatic brain tumors in non-small cell lung cancer patients, vol. 14, pp. 3545-3550, 2015.

We conducted a case-control study to investigate the role of 3 single-nucleotide polymorphisms of the gene encoding transforming growth factor-b1 (TGFB1) in the development of metastatic brain tumors in non-small cell lung cancer patients. The polymorphisms in TGFB1 rs4803455, rs1800469, and rs1800470 were evaluated by polymerase chain reaction-restriction fragment length polymorphism. Odds ratios and their corresponding 95% confidence intervals were used to assess the influence of TGFB1 rs4803455, rs1800469, and rs1800470 on metastatic brain tumors.

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