Role of TGFB1 polymorphism in the development of metastatic brain tumors in non-small cell lung cancer patients
, “Role of TGFB1 polymorphism in the development of metastatic brain tumors in non-small cell lung cancer patients”, vol. 14, pp. 3545-3550, 2015.
We conducted a case-control study to investigate the role of 3 single-nucleotide polymorphisms of the gene encoding transforming growth factor-b1 (TGFB1) in the development of metastatic brain tumors in non-small cell lung cancer patients. The polymorphisms in TGFB1 rs4803455, rs1800469, and rs1800470 were evaluated by polymerase chain reaction-restriction fragment length polymorphism. Odds ratios and their corresponding 95% confidence intervals were used to assess the influence of TGFB1 rs4803455, rs1800469, and rs1800470 on metastatic brain tumors.
