TBARS

Lipid peroxidation and antioxidant capacity of G6PD-deficient patients with A-(202G>A) mutation

L. S. Ondei, Silveira, L. M., Leite, A. A., Souza, D. R. S., Pinhel, M. A. S., Percário, S., O. Júnior, R., and Bonini-Domingos, C. R., Lipid peroxidation and antioxidant capacity of G6PD-deficient patients with A-(202G>A) mutation, vol. 8, pp. 1345-1351, 2009.

Glucose-6-phosphate dehydrogenase (G6PD) deficiency is an enzymopathy in which reduced NADPH concentrations are not maintained, resulting in oxidative damage. We evaluated G6PD activity, oxidative stress levels and Trolox equivalent antioxidant capacity in individuals with the A-(202G>A) mutation for G6PD deficiency. Five hundred and forty-four peripheral blood samples were screened for G6PD deficiency; we also analyzed lipid peroxidation products measured as thiobarbituric acid reactive species and Trolox equivalent antioxidant capacity.

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